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Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Végran F, Boireau W, Simon B, Ryffel B, Connat JL, Kanellopoulos J, Martin F, Rébé C, Apetoh L, Ghiringhelli F. Bruchard M, et al. Among authors: apetoh l. Nat Med. 2013 Jan;19(1):57-64. doi: 10.1038/nm.2999. Epub 2012 Dec 2. Nat Med. 2013. PMID: 23202296
A novel dendritic cell subset involved in tumor immunosurveillance.
Taieb J, Chaput N, Ménard C, Apetoh L, Ullrich E, Bonmort M, Péquignot M, Casares N, Terme M, Flament C, Opolon P, Lecluse Y, Métivier D, Tomasello E, Vivier E, Ghiringhelli F, Martin F, Klatzmann D, Poynard T, Tursz T, Raposo G, Yagita H, Ryffel B, Kroemer G, Zitvogel L. Taieb J, et al. Among authors: apetoh l. Nat Med. 2006 Feb;12(2):214-9. doi: 10.1038/nm1356. Epub 2006 Jan 29. Nat Med. 2006. PMID: 16444265
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Obeid M, Tesniere A, Ghiringhelli F, Fimia GM, Apetoh L, Perfettini JL, Castedo M, Mignot G, Panaretakis T, Casares N, Métivier D, Larochette N, van Endert P, Ciccosanti F, Piacentini M, Zitvogel L, Kroemer G. Obeid M, et al. Among authors: apetoh l. Nat Med. 2007 Jan;13(1):54-61. doi: 10.1038/nm1523. Epub 2006 Dec 24. Nat Med. 2007. PMID: 17187072
Links between innate and cognate tumor immunity.
Ghiringhelli F, Apetoh L, Housseau F, Kroemer G, Zitvogel L. Ghiringhelli F, et al. Among authors: apetoh l. Curr Opin Immunol. 2007 Apr;19(2):224-31. doi: 10.1016/j.coi.2007.02.003. Epub 2007 Feb 15. Curr Opin Immunol. 2007. PMID: 17303400 Review.
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.
Apetoh L, Ghiringhelli F, Tesniere A, Obeid M, Ortiz C, Criollo A, Mignot G, Maiuri MC, Ullrich E, Saulnier P, Yang H, Amigorena S, Ryffel B, Barrat FJ, Saftig P, Levi F, Lidereau R, Nogues C, Mira JP, Chompret A, Joulin V, Clavel-Chapelon F, Bourhis J, André F, Delaloge S, Tursz T, Kroemer G, Zitvogel L. Apetoh L, et al. Nat Med. 2007 Sep;13(9):1050-9. doi: 10.1038/nm1622. Epub 2007 Aug 19. Nat Med. 2007. PMID: 17704786
Immunogenic chemotherapy: discovery of a critical protein through proteomic analyses of tumor cells.
Apetoh L, Obeid M, Tesniere A, Ghiringhelli F, Fimia GM, Piacentini M, Kroemer G, Zitvogel L. Apetoh L, et al. Cancer Genomics Proteomics. 2007 Mar-Apr;4(2):65-70. Cancer Genomics Proteomics. 2007. PMID: 17804868 Review.
Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference.
Chaput N, De Botton S, Obeid M, Apetoh L, Ghiringhelli F, Panaretakis T, Flament C, Zitvogel L, Kroemer G. Chaput N, et al. Among authors: apetoh l. J Mol Med (Berl). 2007 Oct;85(10):1069-76. doi: 10.1007/s00109-007-0214-1. Epub 2007 May 22. J Mol Med (Berl). 2007. PMID: 17891368 Review.
Ecto-calreticulin in immunogenic chemotherapy.
Obeid M, Tesniere A, Panaretakis T, Tufi R, Joza N, van Endert P, Ghiringhelli F, Apetoh L, Chaput N, Flament C, Ullrich E, de Botton S, Zitvogel L, Kroemer G. Obeid M, et al. Among authors: apetoh l. Immunol Rev. 2007 Dec;220:22-34. doi: 10.1111/j.1600-065X.2007.00567.x. Immunol Rev. 2007. PMID: 17979837 Review.
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy.
Apetoh L, Ghiringhelli F, Tesniere A, Criollo A, Ortiz C, Lidereau R, Mariette C, Chaput N, Mira JP, Delaloge S, André F, Tursz T, Kroemer G, Zitvogel L. Apetoh L, et al. Immunol Rev. 2007 Dec;220:47-59. doi: 10.1111/j.1600-065X.2007.00573.x. Immunol Rev. 2007. PMID: 17979839 Review.
Immunological aspects of cancer chemotherapy.
Zitvogel L, Apetoh L, Ghiringhelli F, Kroemer G. Zitvogel L, et al. Among authors: apetoh l. Nat Rev Immunol. 2008 Jan;8(1):59-73. doi: 10.1038/nri2216. Nat Rev Immunol. 2008. PMID: 18097448 Review.
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