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Chromosomal translocations involving the MLL gene: molecular mechanisms.
Aplan PD. Aplan PD. DNA Repair (Amst). 2006 Sep 8;5(9-10):1265-72. doi: 10.1016/j.dnarep.2006.05.034. Epub 2006 Jun 21. DNA Repair (Amst). 2006. PMID: 16797254 Free PMC article. Review.
Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript.
Begley CG, Aplan PD, Davey MP, Nakahara K, Tchorz K, Kurtzberg J, Hershfield MS, Haynes BF, Cohen DI, Waldmann TA, et al. Begley CG, et al. Proc Natl Acad Sci U S A. 1989 Mar;86(6):2031-5. doi: 10.1073/pnas.86.6.2031. Proc Natl Acad Sci U S A. 1989. PMID: 2467296 Free PMC article.
The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif.
Begley CG, Aplan PD, Denning SM, Haynes BF, Waldmann TA, Kirsch IR. Begley CG, et al. Proc Natl Acad Sci U S A. 1989 Dec;86(24):10128-32. doi: 10.1073/pnas.86.24.10128. Proc Natl Acad Sci U S A. 1989. PMID: 2602361 Free PMC article.
Complex MLL rearrangement in a patient with T-cell acute lymphoblastic leukemia.
Chervinsky DS, Sait SN, Nowak NJ, Shows TB, Aplan PD. Chervinsky DS, et al. Genes Chromosomes Cancer. 1995 Sep;14(1):76-84. doi: 10.1002/gcc.2870140114. Genes Chromosomes Cancer. 1995. PMID: 8527389
ML-1 cell line lacks a germline MLL locus.
Strout MP, Mrózek K, Heinonen K, Sait SN, Shows TB, Aplan PD. Strout MP, et al. Genes Chromosomes Cancer. 1996 Jul;16(3):204-10. doi: 10.1002/(SICI)1098-2264(199607)16:3<204::AID-GCC8>3.0.CO;2-2. Genes Chromosomes Cancer. 1996. PMID: 8814454
Molecular biology of acute lymphocytic leukemia.
Thandla S, Aplan PD. Thandla S, et al. Semin Oncol. 1997 Feb;24(1):45-56. Semin Oncol. 1997. PMID: 9045304 Review.
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