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Enzymatic reduction of arsenic compounds in mammalian systems: reduction of arsenate to arsenite by human liver arsenate reductase.
Radabaugh TR, Aposhian HV. Radabaugh TR, et al. Among authors: aposhian hv. Chem Res Toxicol. 2000 Jan;13(1):26-30. doi: 10.1021/tx990115k. Chem Res Toxicol. 2000. PMID: 10649963
DMPS-arsenic challenge test. I: Increased urinary excretion of monomethylarsonic acid in humans given dimercaptopropane sulfonate.
Aposhian HV, Arroyo A, Cebrian ME, del Razo LM, Hurlbut KM, Dart RC, Gonzalez-Ramirez D, Kreppel H, Speisky H, Smith A, Gonsebatt ME, Ostrosky-Wegman P, Aposhian MM. Aposhian HV, et al. Among authors: aposhian mm. J Pharmacol Exp Ther. 1997 Jul;282(1):192-200. J Pharmacol Exp Ther. 1997. PMID: 9223554
Variability in human metabolism of arsenic.
Loffredo CA, Aposhian HV, Cebrian ME, Yamauchi H, Silbergeld EK. Loffredo CA, et al. Among authors: aposhian hv. Environ Res. 2003 Jun;92(2):85-91. doi: 10.1016/s0013-9351(02)00081-6. Environ Res. 2003. PMID: 12854687
Glutathione-S-transferase-omega [MMA(V) reductase] knockout mice: enzyme and arsenic species concentrations in tissues after arsenate administration.
Chowdhury UK, Zakharyan RA, Hernandez A, Avram MD, Kopplin MJ, Aposhian HV. Chowdhury UK, et al. Among authors: aposhian hv. Toxicol Appl Pharmacol. 2006 Nov 1;216(3):446-57. doi: 10.1016/j.taap.2006.06.014. Epub 2006 Jul 7. Toxicol Appl Pharmacol. 2006. PMID: 16930657
Arsenic toxicology: five questions.
Aposhian HV, Aposhian MM. Aposhian HV, et al. Chem Res Toxicol. 2006 Jan;19(1):1-15. doi: 10.1021/tx050106d. Chem Res Toxicol. 2006. PMID: 16411650 Review. No abstract available.
Interactions of sodium selenite, glutathione, arsenic species, and omega class human glutathione transferase.
Zakharyan RA, Tsaprailis G, Chowdhury UK, Hernandez A, Aposhian HV. Zakharyan RA, et al. Among authors: aposhian hv. Chem Res Toxicol. 2005 Aug;18(8):1287-95. doi: 10.1021/tx0500530. Chem Res Toxicol. 2005. PMID: 16097802
A review of the enzymology of arsenic metabolism and a new potential role of hydrogen peroxide in the detoxication of the trivalent arsenic species.
Aposhian HV, Zakharyan RA, Avram MD, Sampayo-Reyes A, Wollenberg ML. Aposhian HV, et al. Toxicol Appl Pharmacol. 2004 Aug 1;198(3):327-35. doi: 10.1016/j.taap.2003.10.027. Toxicol Appl Pharmacol. 2004. PMID: 15276412 Review.
Polymorphisms in the human monomethylarsonic acid (MMA V) reductase/hGSTO1 gene and changes in urinary arsenic profiles.
Marnell LL, Garcia-Vargas GG, Chowdhury UK, Zakharyan RA, Walsh B, Avram MD, Kopplin MJ, Cebrián ME, Silbergeld EK, Aposhian HV. Marnell LL, et al. Among authors: aposhian hv. Chem Res Toxicol. 2003 Dec;16(12):1507-13. doi: 10.1021/tx034149a. Chem Res Toxicol. 2003. PMID: 14680363
The metabolism of inorganic arsenic oxides, gallium arsenide, and arsine: a toxicochemical review.
Carter DE, Aposhian HV, Gandolfi AJ. Carter DE, et al. Among authors: aposhian hv. Toxicol Appl Pharmacol. 2003 Dec 15;193(3):309-34. doi: 10.1016/j.taap.2003.07.009. Toxicol Appl Pharmacol. 2003. PMID: 14678742 Review.
Oxidation and detoxification of trivalent arsenic species.
Aposhian HV, Zakharyan RA, Avram MD, Kopplin MJ, Wollenberg ML. Aposhian HV, et al. Toxicol Appl Pharmacol. 2003 Nov 15;193(1):1-8. doi: 10.1016/s0041-008x(03)00324-7. Toxicol Appl Pharmacol. 2003. PMID: 14613711
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