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meso-2,3-Dimercaptosuccinic acid: chemical, pharmacological and toxicological properties of an orally effective metal chelating agent.
Aposhian HV, Aposhian MM. Aposhian HV, et al. Among authors: aposhian mm. Annu Rev Pharmacol Toxicol. 1990;30:279-306. doi: 10.1146/annurev.pa.30.040190.001431. Annu Rev Pharmacol Toxicol. 1990. PMID: 2160791 Review.
Vitamin C, glutathione, or lipoic acid did not decrease brain or kidney mercury in rats exposed to mercury vapor.
Aposhian HV, Morgan DL, Queen HL, Maiorino RM, Aposhian MM. Aposhian HV, et al. Among authors: aposhian mm. J Toxicol Clin Toxicol. 2003;41(4):339-47. doi: 10.1081/clt-120022000. J Toxicol Clin Toxicol. 2003. PMID: 12870874
Arsenic toxicology: five questions.
Aposhian HV, Aposhian MM. Aposhian HV, et al. Among authors: aposhian mm. Chem Res Toxicol. 2006 Jan;19(1):1-15. doi: 10.1021/tx050106d. Chem Res Toxicol. 2006. PMID: 16411650 Review. No abstract available.
Determination and metabolism of dithiol chelating agents. XV. The meso-2,3-dimercaptosuccinic acid-cysteine (1:2) mixed disulfide, a major urinary metabolite of DMSA in the human, increases the urinary excretion of lead in the rat.
Maiorino RM, Aposhian MM, Xu ZF, Li Y, Polt RL, Aposhian HV. Maiorino RM, et al. Among authors: aposhian mm, aposhian hv. J Pharmacol Exp Ther. 1993 Dec;267(3):1221-6. J Pharmacol Exp Ther. 1993. PMID: 8263783
Occurrence of monomethylarsonous acid in urine of humans exposed to inorganic arsenic.
Aposhian HV, Gurzau ES, Le XC, Gurzau A, Healy SM, Lu X, Ma M, Yip L, Zakharyan RA, Maiorino RM, Dart RC, Tircus MG, Gonzalez-Ramirez D, Morgan DL, Avram D, Aposhian MM. Aposhian HV, et al. Among authors: aposhian mm. Chem Res Toxicol. 2000 Aug;13(8):693-7. doi: 10.1021/tx000114o. Chem Res Toxicol. 2000. PMID: 10956055
DMPS-arsenic challenge test. II. Modulation of arsenic species, including monomethylarsonous acid (MMA(III)), excreted in human urine.
Aposhian HV, Zheng B, Aposhian MM, Le XC, Cebrian ME, Cullen W, Zakharyan RA, Ma M, Dart RC, Cheng Z, Andrewes P, Yip L, O'Malley GF, Maiorino RM, Van Voorhies W, Healy SM, Titcomb A. Aposhian HV, et al. Among authors: aposhian mm. Toxicol Appl Pharmacol. 2000 May 15;165(1):74-83. doi: 10.1006/taap.2000.8922. Toxicol Appl Pharmacol. 2000. PMID: 10814555
DMPS-arsenic challenge test. I: Increased urinary excretion of monomethylarsonic acid in humans given dimercaptopropane sulfonate.
Aposhian HV, Arroyo A, Cebrian ME, del Razo LM, Hurlbut KM, Dart RC, Gonzalez-Ramirez D, Kreppel H, Speisky H, Smith A, Gonsebatt ME, Ostrosky-Wegman P, Aposhian MM. Aposhian HV, et al. Among authors: aposhian mm. J Pharmacol Exp Ther. 1997 Jul;282(1):192-200. J Pharmacol Exp Ther. 1997. PMID: 9223554
Sodium 2,3-dimercapto-1-propanesulfonate (DMPS) treatment does not redistribute lead or mercury to the brain of rat.
Aposhian MM, Maiorino RM, Xu Z, Aposhian HV. Aposhian MM, et al. Toxicology. 1996 May 3;109(1):49-55. doi: 10.1016/0300-483x(96)03308-2. Toxicology. 1996. PMID: 8619252
Mobilization of heavy metals by newer, therapeutically useful chelating agents.
Aposhian HV, Maiorino RM, Gonzalez-Ramirez D, Zuniga-Charles M, Xu Z, Hurlbut KM, Junco-Munoz P, Dart RC, Aposhian MM. Aposhian HV, et al. Among authors: aposhian mm. Toxicology. 1995 Mar 31;97(1-3):23-38. doi: 10.1016/0300-483x(95)02965-b. Toxicology. 1995. PMID: 7716789 Review.
Tissue decorporation of polonium-210 in rats by DMPA.
Aposhian HV, Dart RC, Aposhian MM, Dawson BV. Aposhian HV, et al. Among authors: aposhian mm. Res Commun Chem Pathol Pharmacol. 1987 Nov;58(2):157-71. Res Commun Chem Pathol Pharmacol. 1987. PMID: 2827276
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