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Endoplasmic Reticulum and Mitochondria: Independent Roles and Crosstalk in Fatty Liver Diseases and Hepatic Inflammation.
Blas-García A, Apostolova N, Valls-Bellés V, Esplugues JV. Blas-García A, et al. Among authors: apostolova n. Curr Pharm Des. 2016;22(18):2607-18. doi: 10.2174/1381612822666160204120354. Curr Pharm Des. 2016. PMID: 26845326 Review.
Oxidative stress and mitochondrial dysfunction in atherosclerosis: mitochondria-targeted antioxidants as potential therapy.
Victor VM, Apostolova N, Herance R, Hernandez-Mijares A, Rocha M. Victor VM, et al. Among authors: apostolova n. Curr Med Chem. 2009;16(35):4654-67. doi: 10.2174/092986709789878265. Curr Med Chem. 2009. PMID: 19903143 Review.
Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells.
Blas-García A, Apostolova N, Ballesteros D, Monleón D, Morales JM, Rocha M, Victor VM, Esplugues JV. Blas-García A, et al. Among authors: apostolova n. Hepatology. 2010 Jul;52(1):115-25. doi: 10.1002/hep.23647. Hepatology. 2010. PMID: 20564379
Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells.
Apostolova N, Gomez-Sucerquia LJ, Moran A, Alvarez A, Blas-Garcia A, Esplugues JV. Apostolova N, et al. Br J Pharmacol. 2010 Aug;160(8):2069-84. doi: 10.1111/j.1476-5381.2010.00866.x. Br J Pharmacol. 2010. PMID: 20649602 Free PMC article.
Oxidative stress and endothelial dysfunction in cardiovascular disease: mitochondria-targeted therapeutics.
Rocha M, Apostolova N, Hernandez-Mijares A, Herance R, Victor VM. Rocha M, et al. Among authors: apostolova n. Curr Med Chem. 2010;17(32):3827-41. doi: 10.2174/092986710793205444. Curr Med Chem. 2010. PMID: 20858217 Review.
Twenty years of HIV-1 non-nucleoside reverse transcriptase inhibitors: time to reevaluate their toxicity.
Blas-Garcia A, Esplugues JV, Apostolova N. Blas-Garcia A, et al. Among authors: apostolova n. Curr Med Chem. 2011;18(14):2186-95. doi: 10.2174/092986711795656180. Curr Med Chem. 2011. PMID: 21521162 Review.
Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy.
Apostolova N, Gomez-Sucerquia LJ, Gortat A, Blas-Garcia A, Esplugues JV. Apostolova N, et al. Hepatology. 2011 Sep 2;54(3):1009-19. doi: 10.1002/hep.24459. Epub 2011 Aug 2. Hepatology. 2011. PMID: 21626526
Mitochondria as a pharmacological target: a clue for efficacy and a reason for toxicity.
Apostolova N. Apostolova N. Curr Pharm Des. 2011;17(20):1984-5. doi: 10.2174/138161211796904759. Curr Pharm Des. 2011. PMID: 21718243 No abstract available.
Mitochondrial toxicity in HAART: an overview of in vitro evidence.
Apostolova N, Blas-García A, Esplugues JV. Apostolova N, et al. Curr Pharm Des. 2011;17(20):2130-44. doi: 10.2174/138161211796904731. Curr Pharm Des. 2011. PMID: 21718249 Review.
The mitochondrial effect of N(t)RTI (Nucleos(t)ide Reverse Transcriptase Inhibitors) class of drugs, which has been widely studied, is believed to originate from the inhibitory action of these drugs on DNA polymerase gamma, the enzyme responsible for replication of mitocho …
The mitochondrial effect of N(t)RTI (Nucleos(t)ide Reverse Transcriptase Inhibitors) class of drugs, which has been widely studied, i …
Mitochondrial antioxidants alleviate oxidative and nitrosative stress in a cellular model of sepsis.
Apostolova N, Garcia-Bou R, Hernandez-Mijares A, Herance R, Rocha M, Victor VM. Apostolova N, et al. Pharm Res. 2011 Nov;28(11):2910-9. doi: 10.1007/s11095-011-0528-0. Epub 2011 Jul 23. Pharm Res. 2011. PMID: 21786065
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