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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
2000 1
2003 1
2004 4
2005 4
2006 4
2007 3
2008 3
2009 6
2010 4
2011 5
2012 6
2013 3
2014 5
2015 4
2016 1
2017 2
2018 5
2019 5
2020 3
2021 1
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69 results
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Page 1
Cyclopentane FIT-PNAs: bright RNA sensors.
Tepper O, Zheng H, Appella DH, Yavin E. Tepper O, et al. Among authors: appella dh. Chem Commun (Camb). 2020 Dec 18. doi: 10.1039/d0cc07400d. Online ahead of print. Chem Commun (Camb). 2020. PMID: 33336664
Synthesis and Application of LKγT Peptide Nucleic Acids.
Shank N, George Rosenker KM, Englund EA, Dix AV, Rastede EE, Appella DH. Shank N, et al. Among authors: appella dh. Methods Mol Biol. 2019;1973:131-145. doi: 10.1007/978-1-4939-9216-4_8. Methods Mol Biol. 2019. PMID: 31016699
PNA Clamping in Nucleic Acid Amplification Protocols to Detect Single Nucleotide Mutations Related to Cancer.
Fouz MF, Appella DH. Fouz MF, et al. Among authors: appella dh. Molecules. 2020 Feb 12;25(4):786. doi: 10.3390/molecules25040786. Molecules. 2020. PMID: 32059456 Free PMC article. Review.
Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator.
Miller Jenkins LM, Paine EL, Deshmukh L, Nikolayevskiy H, Lyons GC, Scerba MT, George Rosenker K, Luecke HF, Louis JM, Chertova E, Gorelick RJ, Ott DE, Clore GM, Appella DH. Miller Jenkins LM, et al. Among authors: appella dh. J Am Chem Soc. 2019 May 22;141(20):8327-8338. doi: 10.1021/jacs.9b02743. Epub 2019 May 13. J Am Chem Soc. 2019. PMID: 31042030
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
Clausse V, Tao D, Debnath S, Fang Y, Tagad HD, Wang Y, Sun H, LeClair CA, Mazur SJ, Lane K, Shi ZD, Vasalatiy O, Eells R, Baker LK, Henderson MJ, Webb MR, Shen M, Hall MD, Appella E, Appella DH, Coussens NP. Clausse V, et al. Among authors: appella dh. J Biol Chem. 2019 Nov 15;294(46):17654-17668. doi: 10.1074/jbc.RA119.010201. Epub 2019 Sep 3. J Biol Chem. 2019. PMID: 31481464 Free PMC article.
Allosteric modulation of β-cell M3 muscarinic acetylcholine receptors greatly improves glucose homeostasis in lean and obese mice.
Zhu L, Rossi M, Cohen A, Pham J, Zheng H, Dattaroy D, Mukaibo T, Melvin JE, Langel JL, Hattar S, Matschinsky FM, Appella DH, Doliba NM, Wess J. Zhu L, et al. Among authors: appella dh. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18684-18690. doi: 10.1073/pnas.1904943116. Epub 2019 Aug 26. Proc Natl Acad Sci U S A. 2019. PMID: 31451647 Free PMC article.
The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target.
Nikolayevskiy H, Robello M, Scerba MT, Pasternak EH, Saha M, Hartman TL, Buchholz CA, Buckheit RW Jr, Durell SR, Appella DH. Nikolayevskiy H, et al. Among authors: appella dh. Eur J Med Chem. 2019 Sep 15;178:818-837. doi: 10.1016/j.ejmech.2019.06.020. Epub 2019 Jun 9. Eur J Med Chem. 2019. PMID: 31252286
Non-natural nucleic acids for synthetic biology.
Appella DH. Appella DH. Curr Opin Chem Biol. 2009 Dec;13(5-6):687-96. doi: 10.1016/j.cbpa.2009.09.030. Epub 2009 Oct 29. Curr Opin Chem Biol. 2009. PMID: 19879178 Free PMC article. Review.
An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes.
Helmold Hait S, Hogge CJ, Rahman MA, Ko EJ, Hunegnaw R, Mushtaq Z, Enyindah-Asonye G, Hoang T, Miller Jenkins LM, Appella E, Appella DH, Robert-Guroff M. Helmold Hait S, et al. Among authors: appella dh. J Immunol. 2020 Jun 15;204(12):3315-3328. doi: 10.4049/jimmunol.2000165. Epub 2020 May 11. J Immunol. 2020. PMID: 32393514 Free PMC article.
Targeting DNA G-quadruplex structures with peptide nucleic acids.
Panyutin IG, Onyshchenko MI, Englund EA, Appella DH, Neumann RD. Panyutin IG, et al. Among authors: appella dh. Curr Pharm Des. 2012;18(14):1984-91. doi: 10.2174/138161212799958440. Curr Pharm Des. 2012. PMID: 22376112 Free PMC article. Review.
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