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Androgen Deprivation Therapy and the Risk of Dementia in Patients With Prostate Cancer.
Khosrow-Khavar F, Rej S, Yin H, Aprikian A, Azoulay L. Khosrow-Khavar F, et al. Among authors: aprikian a. J Clin Oncol. 2017 Jan 10;35(2):201-207. doi: 10.1200/JCO.2016.69.6203. Epub 2016 Nov 21. J Clin Oncol. 2017. PMID: 27870566
Patients and Methods Using the United Kingdom's Clinical Practice Research Datalink, we assembled a cohort of 30,903 men newly diagnosed with nonmetastatic prostate cancer between April 1, 1988 and April 30, 2015, and observed them until April 30, 2016. ...Results During …
Patients and Methods Using the United Kingdom's Clinical Practice Research Datalink, we assembled a cohort of 30,903 men newly diagno …
Role of prostate-specific antigen density after applying age-specific prostate-specific antigen reference ranges.
Meshref AW, Bazinet M, Trudel C, Aronson S, Peloquin F, Nachabe M, Dessureault J, Aprikian AG, Begin LR, Elhilali MM. Meshref AW, et al. Among authors: aprikian ag. Urology. 1995 Jun;45(6):972-9. doi: 10.1016/s0090-4295(99)80117-4. Urology. 1995. PMID: 7539562 Clinical Trial.
Of these, 315 cases (56.8%) still had a PSAD of less than 0.15. We performed biopsies in 108 of these 315 and detected only two cancers, for a positive biopsy rate (PBR) of 1.9%. The remaining 240 cases had a PSAD of 0.15 or higher, and we performed biopsies …
Of these, 315 cases (56.8%) still had a PSAD of less than 0.15. We performed biopsies in 108 of these 315 and detected only two cance …
Family history and the risk of prostatic carcinoma in a high risk group of urological patients.
Aprikian AG, Bazinet M, Plante M, Meshref A, Trudel C, Aronson S, Nachabe M, Péloquin F, Déssureault J, Narod S, et al. Aprikian AG, et al. J Urol. 1995 Aug;154(2 Pt 1):404-6. doi: 10.1097/00005392-199508000-00022. J Urol. 1995. PMID: 7541856
MATERIALS AND METHODS: A total of 2,968 consecutive patients referred for prostate cancer detection responded to a questionnaire and underwent transrectal ultrasound examination with or without biopsy. ...CONCLUSIONS: Patients with a family history of prostat …
MATERIALS AND METHODS: A total of 2,968 consecutive patients referred for prostate cancer detection responded to a questionnai …
Use of neoadjuvant androgen deprivation therapy in clinically localized prostate cancer.
Fair WR, Aprikian AG, Cohen D, Sogani P, Reuter V. Fair WR, et al. Among authors: aprikian ag. Clin Invest Med. 1993 Dec;16(6):516-22. Clin Invest Med. 1993. PMID: 8013156 Review.
However, a subset of patients demonstrated marked pathologic regression, so we initiated a nonrandomized but controlled study of neoadjuvant ADT (goserelin acetate and flutamide for 3 months) followed by radical prostatectomy in patients with clinically localized pr …
However, a subset of patients demonstrated marked pathologic regression, so we initiated a nonrandomized but controlled study …
Value of systematic transition zone biopsies in the early detection of prostate cancer.
Bazinet M, Karakiewicz PI, Aprikian AG, Trudel C, Aronson S, Nachabé M, Péloquin F, Dessureault J, Goyal M, Zheng W, Bégin LR, Elhilali MM. Bazinet M, et al. Among authors: aprikian ag. J Urol. 1996 Feb;155(2):605-6. J Urol. 1996. PMID: 8558670 Clinical Trial.
PURPOSE: A prospective study was done to determine the value of performing 2 systematic transition zone biopsies in addition to systematic sextant peripheral zone biopsies for early detection of prostate cancer. ...The same analysis of 552 patients with a negative d …
PURPOSE: A prospective study was done to determine the value of performing 2 systematic transition zone biopsies in addition to syste …
Bombesin specifically induces intracellular calcium mobilization via gastrin-releasing peptide receptors in human prostate cancer cells.
Aprikian AG, Han K, Chevalier S, Bazinet M, Viallet J. Aprikian AG, et al. J Mol Endocrinol. 1996 Jun;16(3):297-306. doi: 10.1677/jme.0.0160297. J Mol Endocrinol. 1996. PMID: 8782088
Molecular characterization of the binding sites performed in PC-3 cells by cross-linking experiments and SDS/PAGE revealed a single radioactive band of 85 kDa. ...This suggests that the bombesin/GRP family of neuropeptides may play a regulatory role in the biology o …
Molecular characterization of the binding sites performed in PC-3 cells by cross-linking experiments and SDS/PAGE revealed a single r …
Characterization of intracellular calcium mobilization by bombesin-related neuropeptides in PC-3 human prostate cancer cells.
Han K, Viallet J, Chevalier S, Zheng W, Bazinet M, Aprikian AG. Han K, et al. Among authors: aprikian ag. Prostate. 1997 Apr 1;31(1):53-60. doi: 10.1002/(sici)1097-0045(19970401)31:1<53::aid-pros9>3.0.co;2-j. Prostate. 1997. PMID: 9108887
RESULTS: Individual neuropeptides induced a rapid rise in [Ca2+]i immediately after stimulation in similar fashion. When two different peptides were administered simultaneously, the [Ca2+]i changes were similar to that produced by each peptide alone. ...However, 6 hrs afte …
RESULTS: Individual neuropeptides induced a rapid rise in [Ca2+]i immediately after stimulation in similar fashion. When two differen …
The indications, rationale, and results of neoadjuvant androgen deprivation in the treatment of prostatic cancer: Memorial Sloan-Kettering Cancer Center results.
Fair WR, Cookson MS, Stroumbakis N, Cohen D, Aprikian AG, Wang Y, Russo P, Soloway SM, Sogani P, Sheinfeld J, Herr H, Dalgabni G, Begg CB, Heston WD, Reuter VE. Fair WR, et al. Among authors: aprikian ag. Urology. 1997 Mar;49(3A Suppl):46-55. doi: 10.1016/s0090-4295(97)00169-6. Urology. 1997. PMID: 9123736 Clinical Trial.
The use of neoadjuvant androgen deprivation therapy (ADT) in conjunction with radical prostatectomy remains a source of controversy. ...METHODS: We report the results of 141 patients, Stage T0-T0, in a Phase II study with concurrent, nonrandomized controls (N = 72) …
The use of neoadjuvant androgen deprivation therapy (ADT) in conjunction with radical prostatectomy remains a source of controversy. …
Morphologic changes induced by neoadjuvant androgen ablation may result in underdetection of positive surgical margins and capsular involvement by prostatic adenocarcinoma.
Bazinet M, Zheng W, Bégin LR, Aprikian AG, Karakiewicz PI, Elhilali MM. Bazinet M, et al. Among authors: aprikian ag. Urology. 1997 May;49(5):721-5. doi: 10.1016/S0090-4295(97)00062-9. Urology. 1997. PMID: 9145977
Prostate cancer: 5. Diagnostic tools for early detection.
Karakiewicz PI, Aprikian AG. Karakiewicz PI, et al. Among authors: aprikian ag. CMAJ. 1998 Nov 3;159(9):1139-46. CMAJ. 1998. PMID: 9835884 Free PMC article. Review. No abstract available.
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