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Angiotensin II induces vascular endothelial growth factor in pancreatic cancer cells through an angiotensin II type 1 receptor and ERK1/2 signaling.
Anandanadesan R, Gong Q, Chipitsyna G, Witkiewicz A, Yeo CJ, Arafat HA. Anandanadesan R, et al. J Gastrointest Surg. 2008 Jan;12(1):57-66. doi: 10.1007/s11605-007-0403-9. Epub 2007 Nov 17. J Gastrointest Surg. 2008. PMID: 18026817
Streptozotocin (STZ) mediates acute upregulation of serum and pancreatic osteopontin (OPN): a novel islet-protective effect of OPN through inhibition of STZ-induced nitric oxide production.
Katakam AK, Chipitsyna G, Gong Q, Vancha AR, Gabbeta J, Arafat HA. Katakam AK, et al. J Endocrinol. 2005 Nov;187(2):237-47. doi: 10.1677/joe.1.06411. J Endocrinol. 2005. PMID: 16293771
Tumor-specific expression and alternative splicing of the COL6A3 gene in pancreatic cancer.
Arafat H, Lazar M, Salem K, Chipitsyna G, Gong Q, Pan TC, Zhang RZ, Yeo CJ, Chu ML. Arafat H, et al. Surgery. 2011 Aug;150(2):306-15. doi: 10.1016/j.surg.2011.05.011. Epub 2011 Jun 30. Surgery. 2011. PMID: 21719059 Free PMC article.
Human epicardial adipose tissue is a source of inflammatory mediators.
Mazurek T, Zhang L, Zalewski A, Mannion JD, Diehl JT, Arafat H, Sarov-Blat L, O'Brien S, Keiper EA, Johnson AG, Martin J, Goldstein BJ, Shi Y. Mazurek T, et al. Circulation. 2003 Nov 18;108(20):2460-6. doi: 10.1161/01.CIR.0000099542.57313.C5. Epub 2003 Oct 27. Circulation. 2003. PMID: 14581396
Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition.
Salem AF, Bonuccelli G, Bevilacqua G, Arafat H, Pestell RG, Sotgia F, Lisanti MP. Salem AF, et al. Cell Cycle. 2011 Nov 1;10(21):3692-700. doi: 10.4161/cc.10.21.17895. Epub 2011 Nov 1. Cell Cycle. 2011. PMID: 22041584 Free PMC article.
Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapies.
Torres MP, Ponnusamy MP, Chakraborty S, Smith LM, Das S, Arafat HA, Batra SK. Torres MP, et al. Mol Cancer Ther. 2010 May;9(5):1419-31. doi: 10.1158/1535-7163.MCT-10-0075. Epub 2010 Apr 27. Mol Cancer Ther. 2010. PMID: 20423995 Free PMC article.
Osteopontin (OPN) isoforms, diabetes, obesity, and cancer; what is one got to do with the other? A new role for OPN.
Sarosiek K, Jones E, Chipitsyna G, Al-Zoubi M, Kang C, Saxena S, Gandhi AV, Sendiky J, Yeo CJ, Arafat HA. Sarosiek K, et al. J Gastrointest Surg. 2015 Apr;19(4):639-50. doi: 10.1007/s11605-014-2735-6. Epub 2015 Jan 13. J Gastrointest Surg. 2015. PMID: 25583441
RAN GTPase and Osteopontin in Pancreatic Cancer.
Saxena S, Gandhi A, Lim PW, Relles D, Sarosiek K, Kang C, Chipitsyna G, Sendecki J, Yeo CJ, Arafat HA. Saxena S, et al. Pancreat Disord Ther. 2013 Apr 1;3(1):113. doi: 10.4172/2165-7092.1000113. Pancreat Disord Ther. 2013. PMID: 24749004 Free PMC article.
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