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PGC-1 coactivators and skeletal muscle adaptations in health and disease.
Arany Z. Arany Z. Curr Opin Genet Dev. 2008 Oct;18(5):426-34. doi: 10.1016/j.gde.2008.07.018. Epub 2008 Sep 7. Curr Opin Genet Dev. 2008. PMID: 18782618 Free PMC article. Review.
Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging.
Das A, Huang GX, Bonkowski MS, Longchamp A, Li C, Schultz MB, Kim LJ, Osborne B, Joshi S, Lu Y, Treviño-Villarreal JH, Kang MJ, Hung TT, Lee B, Williams EO, Igarashi M, Mitchell JR, Wu LE, Turner N, Arany Z, Guarente L, Sinclair DA. Das A, et al. Cell. 2018 Mar 22;173(1):74-89.e20. doi: 10.1016/j.cell.2018.02.008. Cell. 2018. PMID: 29570999 Free PMC article.
Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.
Haq R, Shoag J, Andreu-Perez P, Yokoyama S, Edelman H, Rowe GC, Frederick DT, Hurley AD, Nellore A, Kung AL, Wargo JA, Song JS, Fisher DE, Arany Z, Widlund HR. Haq R, et al. Cancer Cell. 2013 Mar 18;23(3):302-15. doi: 10.1016/j.ccr.2013.02.003. Epub 2013 Mar 7. Cancer Cell. 2013. PMID: 23477830 Free PMC article.
Disconnecting mitochondrial content from respiratory chain capacity in PGC-1-deficient skeletal muscle.
Rowe GC, Patten IS, Zsengeller ZK, El-Khoury R, Okutsu M, Bampoh S, Koulisis N, Farrell C, Hirshman MF, Yan Z, Goodyear LJ, Rustin P, Arany Z. Rowe GC, et al. Cell Rep. 2013 May 30;3(5):1449-56. doi: 10.1016/j.celrep.2013.04.023. Epub 2013 May 23. Cell Rep. 2013. PMID: 23707060 Free PMC article.
PGC-1α induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle.
Rowe GC, Raghuram S, Jang C, Nagy JA, Patten IS, Goyal A, Chan MC, Liu LX, Jiang A, Spokes KC, Beeler D, Dvorak H, Aird WC, Arany Z. Rowe GC, et al. Circ Res. 2014 Aug 15;115(5):504-17. doi: 10.1161/CIRCRESAHA.115.303829. Epub 2014 Jul 9. Circ Res. 2014. PMID: 25009290 Free PMC article.
Running forward: new frontiers in endurance exercise biology.
Rowe GC, Safdar A, Arany Z. Rowe GC, et al. Circulation. 2014 Feb 18;129(7):798-810. doi: 10.1161/CIRCULATIONAHA.113.001590. Circulation. 2014. PMID: 24550551 Free PMC article. Review. No abstract available.
The many roles of PGC-1α in muscle--recent developments.
Chan MC, Arany Z. Chan MC, et al. Metabolism. 2014 Apr;63(4):441-51. doi: 10.1016/j.metabol.2014.01.006. Epub 2014 Jan 17. Metabolism. 2014. PMID: 24559845 Free PMC article. Review.
Endothelial PGC-1α mediates vascular dysfunction in diabetes.
Sawada N, Jiang A, Takizawa F, Safdar A, Manika A, Tesmenitsky Y, Kang KT, Bischoff J, Kalwa H, Sartoretto JL, Kamei Y, Benjamin LE, Watada H, Ogawa Y, Higashikuni Y, Kessinger CW, Jaffer FA, Michel T, Sata M, Croce K, Tanaka R, Arany Z. Sawada N, et al. Cell Metab. 2014 Feb 4;19(2):246-58. doi: 10.1016/j.cmet.2013.12.014. Cell Metab. 2014. PMID: 24506866 Free PMC article.
PGC-1α is dispensable for exercise-induced mitochondrial biogenesis in skeletal muscle.
Rowe GC, El-Khoury R, Patten IS, Rustin P, Arany Z. Rowe GC, et al. PLoS One. 2012;7(7):e41817. doi: 10.1371/journal.pone.0041817. Epub 2012 Jul 24. PLoS One. 2012. PMID: 22848618 Free PMC article.
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