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In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation.
Liao HK, Hatanaka F, Araoka T, Reddy P, Wu MZ, Sui Y, Yamauchi T, Sakurai M, O'Keefe DD, Núñez-Delicado E, Guillen P, Campistol JM, Wu CJ, Lu LF, Esteban CR, Izpisua Belmonte JC. Liao HK, et al. Among authors: araoka t. Cell. 2017 Dec 14;171(7):1495-1507.e15. doi: 10.1016/j.cell.2017.10.025. Epub 2017 Dec 7. Cell. 2017. PMID: 29224783 Free PMC article.
In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.
Suzuki K, Tsunekawa Y, Hernandez-Benitez R, Wu J, Zhu J, Kim EJ, Hatanaka F, Yamamoto M, Araoka T, Li Z, Kurita M, Hishida T, Li M, Aizawa E, Guo S, Chen S, Goebl A, Soligalla RD, Qu J, Jiang T, Fu X, Jafari M, Esteban CR, Berggren WT, Lajara J, Nuñez-Delicado E, Guillen P, Campistol JM, Matsuzaki F, Liu GH, Magistretti P, Zhang K, Callaway EM, Zhang K, Belmonte JC. Suzuki K, et al. Among authors: araoka t. Nature. 2016 Dec 1;540(7631):144-149. doi: 10.1038/nature20565. Epub 2016 Nov 16. Nature. 2016. PMID: 27851729 Free PMC article.
3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors.
Li Z, Araoka T, Wu J, Liao HK, Li M, Lazo M, Zhou B, Sui Y, Wu MZ, Tamura I, Xia Y, Beyret E, Matsusaka T, Pastan I, Rodriguez Esteban C, Guillen I, Guillen P, Campistol JM, Izpisua Belmonte JC. Li Z, et al. Among authors: araoka t. Cell Stem Cell. 2016 Oct 6;19(4):516-529. doi: 10.1016/j.stem.2016.07.016. Epub 2016 Aug 25. Cell Stem Cell. 2016. PMID: 27570066 Free PMC article.
In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.
Ocampo A, Reddy P, Martinez-Redondo P, Platero-Luengo A, Hatanaka F, Hishida T, Li M, Lam D, Kurita M, Beyret E, Araoka T, Vazquez-Ferrer E, Donoso D, Roman JL, Xu J, Rodriguez Esteban C, Nuñez G, Nuñez Delicado E, Campistol JM, Guillen I, Guillen P, Izpisua Belmonte JC. Ocampo A, et al. Among authors: araoka t. Cell. 2016 Dec 15;167(7):1719-1733.e12. doi: 10.1016/j.cell.2016.11.052. Cell. 2016. PMID: 27984723 Free PMC article.
In vivo reprogramming of wound-resident cells generates skin epithelial tissue.
Kurita M, Araoka T, Hishida T, O'Keefe DD, Takahashi Y, Sakamoto A, Sakurai M, Suzuki K, Wu J, Yamamoto M, Hernandez-Benitez R, Ocampo A, Reddy P, Shokhirev MN, Magistretti P, Núñez Delicado E, Eto H, Harii K, Izpisua Belmonte JC. Kurita M, et al. Among authors: araoka t. Nature. 2018 Sep;561(7722):243-247. doi: 10.1038/s41586-018-0477-4. Epub 2018 Sep 5. Nature. 2018. PMID: 30185909 Free PMC article.
Podocytes are lost from glomeruli before completing apoptosis.
Yamamoto K, Okabe M, Tanaka K, Yokoo T, Pastan I, Araoka T, Osafune K, Udagawa T, Koizumi M, Matsusaka T. Yamamoto K, et al. Among authors: araoka t. Am J Physiol Renal Physiol. 2022 Nov 1;323(5):F515-F526. doi: 10.1152/ajprenal.00080.2022. Epub 2022 Sep 1. Am J Physiol Renal Physiol. 2022. PMID: 36049065 Free PMC article.
Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice.
Toyohara T, Mae S, Sueta S, Inoue T, Yamagishi Y, Kawamoto T, Kasahara T, Hoshina A, Toyoda T, Tanaka H, Araoka T, Sato-Otsubo A, Takahashi K, Sato Y, Yamaji N, Ogawa S, Yamanaka S, Osafune K. Toyohara T, et al. Among authors: araoka t. Stem Cells Transl Med. 2015 Sep;4(9):980-92. doi: 10.5966/sctm.2014-0219. Epub 2015 Jul 21. Stem Cells Transl Med. 2015. PMID: 26198166 Free PMC article.
30 results