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Ablation of experimental colon cancer by intratumoral 224Radium-loaded wires is mediated by alpha particles released from atoms which spread in the tumor and can be augmented by chemotherapy.
Reitkopf-Brodutch S, Confino H, Schmidt M, Cooks T, Efrati M, Arazi L, Rath-Wolfson L, Marshak G, Kelson I, Keisari Y. Reitkopf-Brodutch S, et al. Among authors: arazi l. Int J Radiat Biol. 2015 Feb;91(2):179-86. doi: 10.3109/09553002.2015.959666. Epub 2015 Jan 29. Int J Radiat Biol. 2015. PMID: 25179346
Initial Safety and Tumor Control Results From a "First-in-Human" Multicenter Prospective Trial Evaluating a Novel Alpha-Emitting Radionuclide for the Treatment of Locally Advanced Recurrent Squamous Cell Carcinomas of the Skin and Head and Neck.
Popovtzer A, Rosenfeld E, Mizrachi A, Bellia SR, Ben-Hur R, Feliciani G, Sarnelli A, Arazi L, Deutsch L, Kelson I, Keisari Y. Popovtzer A, et al. Among authors: arazi l. Int J Radiat Oncol Biol Phys. 2020 Mar 1;106(3):571-578. doi: 10.1016/j.ijrobp.2019.10.048. Epub 2019 Nov 20. Int J Radiat Oncol Biol Phys. 2020. PMID: 31759075 Free article.
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