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Are patients comfortable consenting to clinical anesthesia research trials on the day of surgery?
Brull R, McCartney CJL, Chan VWS, Chung F, Rawson R. Brull R, et al. Anesth Analg. 2004 Apr;98(4):1106-1110. doi: 10.1213/01.ANE.0000106801.98537.25. Anesth Analg. 2004. PMID: 15041607
Consent for clinical anesthesia research trials is often sought on the day of surgery when patients are most anxious and have little privacy or time for reflection. We conducted a retrospective survey of patients' per
Consent for clinical anesthesia research trials is often sought on the day of surgery when
Ultrasound-guided suprainguinal fascia iliaca compartment block and early postoperative analgesia after total hip arthroplasty: a randomised controlled trial.
Safa B, Trinh H, Lansdown A, McHardy PG, Gollish J, Kiss A, Kaustov L, Choi S. Safa B, et al. Br J Anaesth. 2024 Jul;133(1):146-151. doi: 10.1016/j.bja.2024.04.019. Epub 2024 May 18. Br J Anaesth. 2024. PMID: 38762396 Free PMC article. Clinical Trial.
BACKGROUND: Hip replacement surgery can be painful; postoperative analgesia is crucial for comfort and to facilitate recovery. ...There were no differences in other secondary outcomes including pain scores, opioid-related side-effects, or ability to perform physioth …
BACKGROUND: Hip replacement surgery can be painful; postoperative analgesia is crucial for comfort and to facilitate recovery. …
Consent for Anesthesia Clinical Trials on the Day of Surgery: Patient Attitudes and Perceptions.
Murphy GS, Szokol JW, Avram MJ, Greenberg SB, Shear TD, Vender JS, Landry E. Murphy GS, et al. Anesthesiology. 2016 Jun;124(6):1246-55. doi: 10.1097/ALN.0000000000001107. Anesthesiology. 2016. PMID: 27015153
BACKGROUND: Opportunities for anesthesia research investigators to obtain consent for clinical trials are often restricted to the day of surgery, which may limit the ability of subjects to freely decide about research partic …
BACKGROUND: Opportunities for anesthesia research investigators to obtain consent for clinical trials are …
Effect of combination of remimazolam and sevoflurane on elderly patients' recovery quality from general anesthesia after laparoscopic abdominal surgery: a randomized controlled trial.
Lai X, Liu S, Wang D, Chi Y, Su X, Guo L, Zhang Z, Xie H. Lai X, et al. Perioper Med (Lond). 2025 Feb 13;14(1):20. doi: 10.1186/s13741-025-00501-3. Perioper Med (Lond). 2025. PMID: 39948637 Free PMC article.
Our study aims to investigate the influence of remimazolam combined with sevoflurane for general anesthesia maintenance on postoperative recovery quality in elderly patients undergoing laparoscopic abdominal surgery. ...TRIAL REGISTRATION: Chine …
Our study aims to investigate the influence of remimazolam combined with sevoflurane for general anesthesia maintenance on pos …
Effect of nebulized dexmedetomidine on gag reflex suppression and sedation quality in pediatric patients undergoing gastrointestinal endoscopy: a randomized controlled trial.
Turunc E, Ustun YB, Bilgin S, Kaya C, Koksal E, Dost B. Turunc E, et al. BMC Anesthesiol. 2025 May 3;25(1):227. doi: 10.1186/s12871-025-03106-x. BMC Anesthesiol. 2025. PMID: 40319232 Free PMC article. Clinical Trial.
CONCLUSIONS: Nebulized dexmedetomidine is a safe and effective premedication for pediatric patients undergoing endoscopic procedures, significantly reducing gag and cough reflexes, decreasing anesthetic requirements, and enhancing endoscopist satisfaction. This appr …
CONCLUSIONS: Nebulized dexmedetomidine is a safe and effective premedication for pediatric patients undergoing endoscopic procedur
More Comfortable Enjoyment for Upper Eyelid Blepharoplasty: Optimization of Anesthesia Methods Using Stepwise Local Anesthesia Technique.
Fang M, Zhang B, Ding W, Li G. Fang M, et al. Aesthetic Plast Surg. 2025 Oct;49(19):5559-5566. doi: 10.1007/s00266-025-05020-6. Epub 2025 Jun 30. Aesthetic Plast Surg. 2025. PMID: 40588641 Clinical Trial.
This study aimed to explore a new stepwise local anesthesia method for upper eyelid blepharoplasty, utilizing ropivacaine mixed with lidocaine, stepwise increase in epinephrine concentration infiltration, and stepwise specific anesthesia application during two su
This study aimed to explore a new stepwise local anesthesia method for upper eyelid blepharoplasty, utilizing ropivacaine mixed with …
Interactions between midazolam and remifentanil during monitored anesthesia care.
Avramov MN, Smith I, White PF. Avramov MN, et al. Anesthesiology. 1996 Dec;85(6):1283-9. doi: 10.1097/00000542-199612000-00009. Anesthesiology. 1996. PMID: 8968175 Clinical Trial.
BACKGROUND: Remifentanil, an ultra-short-acting opioid analgesic, may be useful as an intravenous adjuvant to local anesthesia for treating patient discomfort and pain during monitored anesthesia care (MAC). ...Side effects and patient satisfaction wer …
BACKGROUND: Remifentanil, an ultra-short-acting opioid analgesic, may be useful as an intravenous adjuvant to local anesthesia for tr …
Hindu Spiritual Music for Perioperative Anxiolysis and Stress Modulation: An Open-Label, Randomized Comparative Trial in Lower Limb Surgery Patients.
Jain A, Verma B, Saunakiya P, Agarwal S, Agarwal P, Gupta P, Thakur C. Jain A, et al. Cureus. 2025 Mar 16;17(3):e80642. doi: 10.7759/cureus.80642. eCollection 2025 Mar. Cureus. 2025. PMID: 40099310 Free PMC article.
Objective This study aimed to evaluate the impact of Hindu religious music compared to patient-selected instrumental music on intraoperative anxiety, stress response, and patient satisfaction in individuals undergoing lower limb surgery under regional anes
Objective This study aimed to evaluate the impact of Hindu religious music compared to patient-selected instrumental music on intraop …