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Kv7 channels can function without constitutive calmodulin tethering.
Gómez-Posada JC, Aivar P, Alberdi A, Alaimo A, Etxeberría A, Fernández-Orth J, Zamalloa T, Roura-Ferrer M, Villace P, Areso P, Casis O, Villarroel A. Gómez-Posada JC, et al. Among authors: Areso P. PLoS One. 2011;6(9):e25508. doi: 10.1371/journal.pone.0025508. Epub 2011 Sep 28. PLoS One. 2011. PMID: 21980481 Free PMC article.
Differential Regulation of PI(4,5)P2 Sensitivity of Kv7.2 and Kv7.3 Channels by Calmodulin.
Gomis-Perez C, Soldovieri MV, Malo C, Ambrosino P, Taglialatela M, Areso P, Villarroel A. Gomis-Perez C, et al. Among authors: Areso P. Front Mol Neurosci. 2017 May 1;10:117. doi: 10.3389/fnmol.2017.00117. eCollection 2017. Front Mol Neurosci. 2017. PMID: 28507506 Free PMC article.
Uncoupling PIP2-calmodulin regulation of Kv7.2 channels by an assembly destabilizing epileptogenic mutation.
Alberdi A, Gomis-Perez C, Bernardo-Seisdedos G, Alaimo A, Malo C, Aldaregia J, Lopez-Robles C, Areso P, Butz E, Wahl-Schott C, Villarroel A. Alberdi A, et al. Among authors: Areso P. J Cell Sci. 2015 Nov 1;128(21):4014-23. doi: 10.1242/jcs.176420. Epub 2015 Sep 10. J Cell Sci. 2015. PMID: 26359296 Free article.
An unconventional calmodulin-anchoring site within the AB module of Kv7.2 channels.
Gomis-Perez C, Alaimo A, Fernandez-Orth J, Alberdi A, Aivar-Mateo P, Bernardo-Seisdedos G, Malo C, Areso P, Felipe A, Villarroel A. Gomis-Perez C, et al. Among authors: Areso P. J Cell Sci. 2015 Aug 15;128(16):3155-63. doi: 10.1242/jcs.174128. Epub 2015 Jul 6. J Cell Sci. 2015. PMID: 26148514 Free article.
The ever changing moods of calmodulin: how structural plasticity entails transductional adaptability.
Villarroel A, Taglialatela M, Bernardo-Seisdedos G, Alaimo A, Agirre J, Alberdi A, Gomis-Perez C, Soldovieri MV, Ambrosino P, Malo C, Areso P. Villarroel A, et al. Among authors: Areso P. J Mol Biol. 2014 Jul 29;426(15):2717-35. doi: 10.1016/j.jmb.2014.05.016. Epub 2014 May 22. J Mol Biol. 2014. PMID: 24857860 Review.
Pivoting between calmodulin lobes triggered by calcium in the Kv7.2/calmodulin complex.
Alaimo A, Alberdi A, Gomis-Perez C, Fernández-Orth J, Bernardo-Seisdedos G, Malo C, Millet O, Areso P, Villarroel A. Alaimo A, et al. Among authors: Areso P. PLoS One. 2014 Jan 28;9(1):e86711. doi: 10.1371/journal.pone.0086711. eCollection 2014. PLoS One. 2014. PMID: 24489773 Free PMC article.
Cooperativity between calmodulin-binding sites in Kv7.2 channels.
Alaimo A, Alberdi A, Gomis-Perez C, Fernández-Orth J, Gómez-Posada JC, Areso P, Villarroel A. Alaimo A, et al. Among authors: Areso P. J Cell Sci. 2013 Jan 1;126(Pt 1):244-53. doi: 10.1242/jcs.114082. Epub 2012 Nov 30. J Cell Sci. 2013. PMID: 23203804 Free article.
A pore residue of the KCNQ3 potassium M-channel subunit controls surface expression.
Gómez-Posada JC, Etxeberría A, Roura-Ferrer M, Areso P, Masin M, Murrell-Lagnado RD, Villarroel A. Gómez-Posada JC, et al. Among authors: Areso P. J Neurosci. 2010 Jul 7;30(27):9316-23. doi: 10.1523/JNEUROSCI.0851-10.2010. J Neurosci. 2010. PMID: 20610766 Free PMC article.
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