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GABAA receptor signalling mechanisms revealed by structural pharmacology.
Masiulis S, Desai R, Uchański T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR. Masiulis S, et al. Among authors: aricescu ar. Nature. 2019 Jan;565(7740):454-459. doi: 10.1038/s41586-018-0832-5. Epub 2019 Jan 2. Nature. 2019. PMID: 30602790 Free PMC article.
Crystal structure of a human GABAA receptor.
Miller PS, Aricescu AR. Miller PS, et al. Among authors: aricescu ar. Nature. 2014 Aug 21;512(7514):270-5. doi: 10.1038/nature13293. Epub 2014 Jun 8. Nature. 2014. PMID: 24909990 Free PMC article.
Initiation of T cell signaling by CD45 segregation at 'close contacts'.
Chang VT, Fernandes RA, Ganzinger KA, Lee SF, Siebold C, McColl J, Jönsson P, Palayret M, Harlos K, Coles CH, Jones EY, Lui Y, Huang E, Gilbert RJC, Klenerman D, Aricescu AR, Davis SJ. Chang VT, et al. Among authors: aricescu ar. Nat Immunol. 2016 May;17(5):574-582. doi: 10.1038/ni.3392. Epub 2016 Mar 21. Nat Immunol. 2016. PMID: 26998761 Free PMC article.
Structural basis for GABAA receptor potentiation by neurosteroids.
Miller PS, Scott S, Masiulis S, De Colibus L, Pardon E, Steyaert J, Aricescu AR. Miller PS, et al. Among authors: aricescu ar. Nat Struct Mol Biol. 2017 Nov;24(11):986-992. doi: 10.1038/nsmb.3484. Epub 2017 Oct 9. Nat Struct Mol Biol. 2017. PMID: 28991263 Free PMC article.
Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer.
Laverty D, Desai R, Uchański T, Masiulis S, Stec WJ, Malinauskas T, Zivanov J, Pardon E, Steyaert J, Miller KW, Aricescu AR. Laverty D, et al. Among authors: aricescu ar. Nature. 2019 Jan;565(7740):516-520. doi: 10.1038/s41586-018-0833-4. Epub 2019 Jan 2. Nature. 2019. PMID: 30602789 Free PMC article.
A structural perspective on GABAA receptor pharmacology.
Scott S, Aricescu AR. Scott S, et al. Among authors: aricescu ar. Curr Opin Struct Biol. 2019 Feb;54:189-197. doi: 10.1016/j.sbi.2019.03.023. Epub 2019 May 23. Curr Opin Struct Biol. 2019. PMID: 31129381 Review.
76 results