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p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia.
Hoshino A, Matoba S, Iwai-Kanai E, Nakamura H, Kimata M, Nakaoka M, Katamura M, Okawa Y, Ariyoshi M, Mita Y, Ikeda K, Ueyama T, Okigaki M, Matsubara H. Hoshino A, et al. Among authors: ariyoshi m. J Mol Cell Cardiol. 2012 Jan;52(1):175-84. doi: 10.1016/j.yjmcc.2011.10.008. Epub 2011 Oct 18. J Mol Cell Cardiol. 2012. PMID: 22044588
p53 promotes cardiac dysfunction in diabetic mellitus caused by excessive mitochondrial respiration-mediated reactive oxygen species generation and lipid accumulation.
Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A, Nakaoka M, Katamura M, Okawa Y, Ariyoshi M, Mita Y, Ikeda K, Okigaki M, Adachi S, Tanaka H, Takamatsu T, Matsubara H. Nakamura H, et al. Among authors: ariyoshi m. Circ Heart Fail. 2012 Jan;5(1):106-15. doi: 10.1161/CIRCHEARTFAILURE.111.961565. Epub 2011 Nov 9. Circ Heart Fail. 2012. PMID: 22075967
Activation of PPAR-α in the early stage of heart failure maintained myocardial function and energetics in pressure-overload heart failure.
Kaimoto S, Hoshino A, Ariyoshi M, Okawa Y, Tateishi S, Ono K, Uchihashi M, Fukai K, Iwai-Kanai E, Matoba S. Kaimoto S, et al. Among authors: ariyoshi m. Am J Physiol Heart Circ Physiol. 2017 Feb 1;312(2):H305-H313. doi: 10.1152/ajpheart.00553.2016. Epub 2016 Dec 23. Am J Physiol Heart Circ Physiol. 2017. PMID: 28011586 Free article.
D-Glutamate is metabolized in the heart mitochondria.
Ariyoshi M, Katane M, Hamase K, Miyoshi Y, Nakane M, Hoshino A, Okawa Y, Mita Y, Kaimoto S, Uchihashi M, Fukai K, Ono K, Tateishi S, Hato D, Yamanaka R, Honda S, Fushimura Y, Iwai-Kanai E, Ishihara N, Mita M, Homma H, Matoba S. Ariyoshi M, et al. Sci Rep. 2017 Mar 7;7:43911. doi: 10.1038/srep43911. Sci Rep. 2017. PMID: 28266638 Free PMC article.
Cardiac-Specific Bdh1 Overexpression Ameliorates Oxidative Stress and Cardiac Remodeling in Pressure Overload-Induced Heart Failure.
Uchihashi M, Hoshino A, Okawa Y, Ariyoshi M, Kaimoto S, Tateishi S, Ono K, Yamanaka R, Hato D, Fushimura Y, Honda S, Fukai K, Higuchi Y, Ogata T, Iwai-Kanai E, Matoba S. Uchihashi M, et al. Among authors: ariyoshi m. Circ Heart Fail. 2017 Dec;10(12):e004417. doi: 10.1161/CIRCHEARTFAILURE.117.004417. Circ Heart Fail. 2017. PMID: 29242353
Pyk2 aggravates hypoxia-induced pulmonary hypertension by activating HIF-1α.
Fukai K, Nakamura A, Hoshino A, Nakanishi N, Okawa Y, Ariyoshi M, Kaimoto S, Uchihashi M, Ono K, Tateishi S, Ikeda K, Ogata T, Ueyama T, Matoba S. Fukai K, et al. Among authors: ariyoshi m. Am J Physiol Heart Circ Physiol. 2015 Apr 15;308(8):H951-9. doi: 10.1152/ajpheart.00770.2014. Epub 2015 Feb 6. Am J Physiol Heart Circ Physiol. 2015. PMID: 25659487 Free article.
141 results