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Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations.
Pellagatti A, Armstrong RN, Steeples V, Sharma E, Repapi E, Singh S, Sanchi A, Radujkovic A, Horn P, Dolatshad H, Roy S, Broxholme J, Lockstone H, Taylor S, Giagounidis A, Vyas P, Schuh A, Hamblin A, Papaemmanuil E, Killick S, Malcovati L, Hennrich ML, Gavin AC, Ho AD, Luft T, Hellström-Lindberg E, Cazzola M, Smith CWJ, Smith S, Boultwood J. Pellagatti A, et al. Among authors: armstrong rn. Blood. 2018 Sep 20;132(12):1225-1240. doi: 10.1182/blood-2018-04-843771. Epub 2018 Jun 21. Blood. 2018. PMID: 29930011 Free PMC article.
The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.
Yip BH, Steeples V, Repapi E, Armstrong RN, Llorian M, Roy S, Shaw J, Dolatshad H, Taylor S, Verma A, Bartenstein M, Vyas P, Cross NC, Malcovati L, Cazzola M, Hellström-Lindberg E, Ogawa S, Smith CW, Pellagatti A, Boultwood J. Yip BH, et al. Among authors: armstrong rn. J Clin Invest. 2017 Jun 1;127(6):2206-2221. doi: 10.1172/JCI91363. Epub 2017 Apr 24. J Clin Invest. 2017. PMID: 28436936 Free PMC article.
Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1-mutant myelodysplastic syndromes.
Dolatshad H, Pellagatti A, Liberante FG, Llorian M, Repapi E, Steeples V, Roy S, Scifo L, Armstrong RN, Shaw J, Yip BH, Killick S, Kušec R, Taylor S, Mills KI, Savage KI, Smith CW, Boultwood J. Dolatshad H, et al. Among authors: armstrong rn. Leukemia. 2016 Dec;30(12):2322-2331. doi: 10.1038/leu.2016.149. Epub 2016 May 23. Leukemia. 2016. PMID: 27211273 Free PMC article.
Response of high-risk MDS to azacitidine and lenalidomide is impacted by baseline and acquired mutations in a cluster of three inositide-specific genes.
Follo MY, Pellagatti A, Armstrong RN, Ratti S, Mongiorgi S, De Fanti S, Bochicchio MT, Russo D, Gobbi M, Miglino M, Parisi S, Martinelli G, Cavo M, Luiselli D, McCubrey JA, Suh PG, Manzoli L, Boultwood J, Finelli C, Cocco L. Follo MY, et al. Among authors: armstrong rn. Leukemia. 2019 Sep;33(9):2276-2290. doi: 10.1038/s41375-019-0416-x. Epub 2019 Feb 20. Leukemia. 2019. PMID: 30787430 Free PMC article.
The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.
Yip BH, Steeples V, Repapi E, Armstrong RN, Llorian M, Roy S, Shaw J, Dolatshad H, Taylor S, Verma A, Bartenstein M, Vyas P, Cross NC, Malcovati L, Cazzola M, Hellström-Lindberg E, Ogawa S, Smith CW, Pellagatti A, Boultwood J. Yip BH, et al. Among authors: armstrong rn. J Clin Invest. 2017 Sep 1;127(9):3557. doi: 10.1172/JCI96202. Epub 2017 Sep 1. J Clin Invest. 2017. PMID: 28862641 Free PMC article. No abstract available.
Genome-wide profiling of methylation identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes.
del Rey M, O'Hagan K, Dellett M, Aibar S, Colyer HA, Alonso ME, Díez-Campelo M, Armstrong RN, Sharpe DJ, Gutiérrez NC, García JL, De Las Rivas J, Mills KI, Hernández-Rivas JM. del Rey M, et al. Among authors: armstrong rn. Leukemia. 2013 Mar;27(3):610-8. doi: 10.1038/leu.2012.253. Epub 2012 Aug 31. Leukemia. 2013. PMID: 22936014
Germline PTPN13 mutations in patients with bone marrow failure and acute lymphoblastic leukemia.
Moshiri H, Cabrera Riofrío DA, Lim YJ, Lauhasurayotin S, Manisterski M, Elhasid R, Bonilla FA, Dhanraj S, Armstrong RN, Li H, Scherer SW, Hernández-Hernández A, Dror Y. Moshiri H, et al. Among authors: armstrong rn. Leukemia. 2022 Aug;36(8):2132-2135. doi: 10.1038/s41375-022-01610-4. Epub 2022 May 28. Leukemia. 2022. PMID: 35643866 No abstract available.
123 results