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A sensitive technique for the detection of the alpha 7 neuronal nicotinic acetylcholine receptor antagonist, methyllycaconitine, in rat plasma and brain.
Turek JW, Kang CH, Campbell JE, Arneric SP, Sullivan JP. Turek JW, et al. J Neurosci Methods. 1995 Sep-Oct;61(1-2):113-8. doi: 10.1016/0165-0270(95)00032-p. J Neurosci Methods. 1995. PMID: 8618408
A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization.
Hurst RS, Hajós M, Raggenbass M, Wall TM, Higdon NR, Lawson JA, Rutherford-Root KL, Berkenpas MB, Hoffmann WE, Piotrowski DW, Groppi VE, Allaman G, Ogier R, Bertrand S, Bertrand D, Arneric SP. Hurst RS, et al. J Neurosci. 2005 Apr 27;25(17):4396-405. doi: 10.1523/JNEUROSCI.5269-04.2005. J Neurosci. 2005. PMID: 15858066 Free PMC article.
Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo.
Briggs CA, Anderson DJ, Brioni JD, Buccafusco JJ, Buckley MJ, Campbell JE, Decker MW, Donnelly-Roberts D, Elliott RL, Gopalakrishnan M, Holladay MW, Hui YH, Jackson WJ, Kim DJ, Marsh KC, O'Neill A, Prendergast MA, Ryther KB, Sullivan JP, Arneric SP. Briggs CA, et al. Pharmacol Biochem Behav. 1997 May-Jun;57(1-2):231-41. doi: 10.1016/s0091-3057(96)00354-1. Pharmacol Biochem Behav. 1997. PMID: 9164577
Synthesis and structure-activity relationships of pyridine-modified analogs of 3-[2-((S)-pyrrolidinyl)methoxy]pyridine, A-84543, a potent nicotinic acetylcholine receptor agonist.
Lin NH, Gunn DE, Li Y, He Y, Bai H, Ryther KB, Kuntzweiler T, Donnelly-Roberts DL, Anderson DJ, Campbell JE, Sullivan JP, Arneric SP, Holladay MW. Lin NH, et al. Bioorg Med Chem Lett. 1998 Feb 3;8(3):249-54. doi: 10.1016/s0960-894x(98)00019-5. Bioorg Med Chem Lett. 1998. PMID: 9871663
Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice.
Decker MW, Bannon AW, Buckley MJ, Kim DJ, Holladay MW, Ryther KB, Lin NH, Wasicak JT, Williams M, Arneric SP. Decker MW, et al. Eur J Pharmacol. 1998 Apr 3;346(1):23-33. doi: 10.1016/s0014-2999(98)00042-9. Eur J Pharmacol. 1998. PMID: 9617748
Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors.
Holladay MW, Wasicak JT, Lin NH, He Y, Ryther KB, Bannon AW, Buckley MJ, Kim DJ, Decker MW, Anderson DJ, Campbell JE, Kuntzweiler TA, Donnelly-Roberts DL, Piattoni-Kaplan M, Briggs CA, Williams M, Arneric SP. Holladay MW, et al. J Med Chem. 1998 Feb 12;41(4):407-12. doi: 10.1021/jm9706224. J Med Chem. 1998. PMID: 9484491
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