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1983 4
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Page 1
Cell-free biosynthesis of arphamenine A.
Okuyama A, Ohuchi S, Tanaka T, Aoyagi T, Umezawa H. Okuyama A, et al. Biochem Int. 1986 Mar;12(3):485-91. Biochem Int. 1986. PMID: 3707594
Arphamenine A was synthesized in a cell-free system obtained from the arphamenine-producing strain, Chromobacterium violaceum BMG361-CF4. L-[14C]-phenylalanine was converted to beta-phenylpyruvic acid by phenylalanine amino-transferase obtained from the 10,000 x g s
Arphamenine A was synthesized in a cell-free system obtained from the arphamenine-producing strain, Chromobacterium violaceum
Collagen production in cardiac fibroblasts during inhibition of aminopeptidase B.
Lijnen PJ, Petrov VV, Turner M, Fagard RH. Lijnen PJ, et al. J Renin Angiotensin Aldosterone Syst. 2005 Sep;6(2):69-77. doi: 10.3317/jraas.2005.012. J Renin Angiotensin Aldosterone Syst. 2005. PMID: 16470485 Free article.
OBJECTIVE: To determine whether the aminopeptidase B inhibitor, arphamenine A, could affect collagen production and expression in control and TGF-ss1-treated cardiac fibroblasts. ...Lysyl oxidase, MMP-1 and MMP-2 activity were inhibited by arphamenine A in the condi …
OBJECTIVE: To determine whether the aminopeptidase B inhibitor, arphamenine A, could affect collagen production and expression in con …
Synthesis of arphamenine A and epi-arphamenine A.
Umezawa H, Nakamura T, Fukatsu S, Aoyagi T, Tatsuta K. Umezawa H, et al. J Antibiot (Tokyo). 1983 Dec;36(12):1787-8. doi: 10.7164/antibiotics.36.1787. J Antibiot (Tokyo). 1983. PMID: 6662821 Free article. No abstract available.
Reversal of angiotensin II-stimulated collagen gel contraction in cardiac fibroblasts by aminopeptidase inhibition.
Lijnen PJ, Petrov VV, Diaz-Araya G, Fagard RH. Lijnen PJ, et al. J Cardiovasc Pharmacol. 2005 Jan;45(1):68-73. doi: 10.1097/00005344-200501000-00012. J Cardiovasc Pharmacol. 2005. PMID: 15613982
These fibroblasts were then further incubated in a floating collagen gel lattice with the tested products (angiotensin II, bestatin, leuhistin, or arphamenine A) for 3 days in DMEM without FBS. The contraction of the collagen gel lattice by cardiac fibroblasts was determin …
These fibroblasts were then further incubated in a floating collagen gel lattice with the tested products (angiotensin II, bestatin, leuhist …
Inhibitory effect of arphamenine A on intestinal dipeptide transport.
Enjoh M, Hashimoto K, Arai S, Shimizu M. Enjoh M, et al. Biosci Biotechnol Biochem. 1996 Nov;60(11):1893-5. doi: 10.1271/bbb.60.1893. Biosci Biotechnol Biochem. 1996. PMID: 8987870 Free article.
Arphamenine A, an Arg-Phe analog without a peptide bond, has been reported to be a possible inhibitor of the peptide transporter [H. ...Adibi, FASEB J., 8, 753 (1994)]. The present study demonstrated that arphamenine A is not a real inhibitor, but is a substrate for
Arphamenine A, an Arg-Phe analog without a peptide bond, has been reported to be a possible inhibitor of the peptide transporter [H.
Chromobacterium violaceum: a review of pharmacological and industiral perspectives.
Durán N, Menck CF. Durán N, et al. Crit Rev Microbiol. 2001;27(3):201-22. doi: 10.1080/20014091096747. Crit Rev Microbiol. 2001. PMID: 11596879 Review.
Besides violacein, C. violaceum produces other antibiotics, such as aerocyanidin and aerocavin, which exhibit in vitro activity against both gram-negative and gram-positive bacteria. 3,6-Dihydroxyindoxazene and Y-TO678h exhibit a selective activity against gram-negative bacteria. …
Besides violacein, C. violaceum produces other antibiotics, such as aerocyanidin and aerocavin, which exhibit in vitro activity against both …
Arginine-aminopeptidase in rat cardiac fibroblastic cells participates in angiotensin peptide turnover.
Petrov VV, Fagard RH, Lijnen PJ. Petrov VV, et al. Cardiovasc Res. 2004 Mar 1;61(4):724-35. doi: 10.1016/j.cardiores.2003.12.003. Cardiovasc Res. 2004. PMID: 14985069
RESULTS: Arginine-aminopeptidase found in cardiac fibroblasts (Fb) was arginine and lysine specific, sensitive to various aminopeptidase (AP) inhibitors and to the inhibitor of metalloproteases, 1.10-phenatroline. Experiments with arphamenine A, a specific inhibitor of ami …
RESULTS: Arginine-aminopeptidase found in cardiac fibroblasts (Fb) was arginine and lysine specific, sensitive to various aminopeptidase (AP …
Separation of enkephalin-degrading enzymes from longitudinal muscle layer of bovine small intestine. Enzyme inhibition by arphamenine A.
Hazato T, Shimamura M, Kase R, Iijima M, Katayama T. Hazato T, et al. Biochem Pharmacol. 1985 Sep 1;34(17):3179-83. doi: 10.1016/0006-2952(85)90166-2. Biochem Pharmacol. 1985. PMID: 3899121
Several protease inhibitors of microbial origin, and synthetic compounds, were tested for their abilities to inhibit these enkephalin-degrading enzymes. Among them, arphamenine A, a new potent inhibitor for aminopeptidase B, was shown to be a useful compound in inhibiting …
Several protease inhibitors of microbial origin, and synthetic compounds, were tested for their abilities to inhibit these enkephalin-degrad …
58 results