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Simulations of the regulatory ACT domain of human phenylalanine hydroxylase (PAH) unveil its mechanism of phenylalanine binding.
J Biol Chem. 2018 Dec 21;293(51):19532-19543. doi: 10.1074/jbc.RA118.004909. Epub 2018 Oct 4.
J Biol Chem. 2018.
PMID: 30287685
Free PMC article.
Biophysical characterization of full-length human phenylalanine hydroxylase provides a deeper understanding of its quaternary structure equilibrium.
Arturo EC, Gupta K, Hansen MR, Borne E, Jaffe EK.
Arturo EC, et al.
J Biol Chem. 2019 Jun 28;294(26):10131-10145. doi: 10.1074/jbc.RA119.008294. Epub 2019 May 10.
J Biol Chem. 2019.
PMID: 31076506
Free PMC article.
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Manipulation of a cation-π sandwich reveals conformational flexibility in phenylalanine hydroxylase.
Arturo EC, Merkel GW, Hansen MR, Lisowski S, Almeida D, Gupta K, Jaffe EK.
Arturo EC, et al.
Biochimie. 2021 Apr;183:63-77. doi: 10.1016/j.biochi.2020.11.011. Epub 2020 Nov 19.
Biochimie. 2021.
PMID: 33221376
Free PMC article.
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First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer.
Arturo EC, Gupta K, Héroux A, Stith L, Cross PJ, Parker EJ, Loll PJ, Jaffe EK.
Arturo EC, et al.
Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2394-9. doi: 10.1073/pnas.1516967113. Epub 2016 Feb 16.
Proc Natl Acad Sci U S A. 2016.
PMID: 26884182
Free PMC article.
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Structural basis of the transcriptional regulation of the proline utilization regulon by multifunctional PutA.
Zhou Y, Larson JD, Bottoms CA, Arturo EC, Henzl MT, Jenkins JL, Nix JC, Becker DF, Tanner JJ.
Zhou Y, et al. Among authors: arturo ec.
J Mol Biol. 2008 Aug 1;381(1):174-88. doi: 10.1016/j.jmb.2008.05.084. Epub 2008 Jun 7.
J Mol Biol. 2008.
PMID: 18586269
Free PMC article.
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Lifted Up from Lockdown.
Arturo EC, Saphire EO.
Arturo EC, et al.
Cell. 2020 Oct 1;183(1):1-3. doi: 10.1016/j.cell.2020.09.027.
Cell. 2020.
PMID: 33007260
Free PMC article.
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