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Endogenous gene and protein expression of drug-transporting proteins in cell lines routinely used in drug discovery programs.
Ahlin G, Hilgendorf C, Karlsson J, Szigyarto CA, Uhlén M, Artursson P. Ahlin G, et al. Among authors: artursson p. Drug Metab Dispos. 2009 Dec;37(12):2275-83. doi: 10.1124/dmd.109.028654. Epub 2009 Sep 9. Drug Metab Dispos. 2009. PMID: 19741037
Cell cultures as models for drug absorption across the intestinal mucosa.
Artursson P. Artursson P. Crit Rev Ther Drug Carrier Syst. 1991;8(4):305-30. Crit Rev Ther Drug Carrier Syst. 1991. PMID: 1769065 Review.
Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein.
Karlsson J, Kuo SM, Ziemniak J, Artursson P. Karlsson J, et al. Among authors: artursson p. Br J Pharmacol. 1993 Nov;110(3):1009-16. doi: 10.1111/j.1476-5381.1993.tb13914.x. Br J Pharmacol. 1993. PMID: 7905337 Free PMC article.
The secretion of celiprolol was inhibited by substrates for P-glycoprotein (vinblastine, verapamil and nifedipine) and either inhibited or stimulated by typical substrates for the renal organic cation-H+ exchanger (cimetidine, N1-methylnicotinamide, tetraethylammonium and …
The secretion of celiprolol was inhibited by substrates for P-glycoprotein (vinblastine, verapamil and nifedipine) and either inhibit …
Correlation of drug absorption with molecular surface properties.
Palm K, Luthman K, Ungell AL, Strandlund G, Artursson P. Palm K, et al. Among authors: artursson p. J Pharm Sci. 1996 Jan;85(1):32-9. doi: 10.1021/js950285r. J Pharm Sci. 1996. PMID: 8926580
Chitosans as absorption enhancers for poorly absorbable drugs. 1: Influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial (Caco-2) cells.
Schipper NG, Vårum KM, Artursson P. Schipper NG, et al. Among authors: artursson p. Pharm Res. 1996 Nov;13(11):1686-92. doi: 10.1023/a:1016444808000. Pharm Res. 1996. PMID: 8956335
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