Ashcroft FM - Search Results

1

Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion.

Freeman H, Shimomura K, Horner E, Cox RD, Ashcroft FM. Freeman H, et al. Among authors: ashcroft fm. Cell Metab. 2006 Jan;3(1):35-45. doi: 10.1016/j.cmet.2005.10.008. Cell Metab. 2006. PMID: 16399503 Free article.

2

A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.

Toye AA, Lippiat JD, Proks P, Shimomura K, Bentley L, Hugill A, Mijat V, Goldsworthy M, Moir L, Haynes A, Quarterman J, Freeman HC, Ashcroft FM, Cox RD. Toye AA, et al. Among authors: ashcroft fm. Diabetologia. 2005 Apr;48(4):675-86. doi: 10.1007/s00125-005-1680-z. Epub 2005 Feb 24. Diabetologia. 2005. PMID: 15729571 Free article.

3

Mutations at the same residue (R50) of Kir6.2 (KCNJ11) that cause neonatal diabetes produce different functional effects.

Shimomura K, Girard CA, Proks P, Nazim J, Lippiat JD, Cerutti F, Lorini R, Ellard S, Hattersley AT, Barbetti F, Ashcroft FM. Shimomura K, et al. Among authors: ashcroft fm. Diabetes. 2006 Jun;55(6):1705-12. doi: 10.2337/db05-1640. Diabetes. 2006. PMID: 16731833

4

Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice.

Freeman HC, Hugill A, Dear NT, Ashcroft FM, Cox RD. Freeman HC, et al. Among authors: ashcroft fm. Diabetes. 2006 Jul;55(7):2153-6. doi: 10.2337/db06-0358. Diabetes. 2006. PMID: 16804088

5

Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes.

Girard CA, Shimomura K, Proks P, Absalom N, Castano L, Perez de Nanclares G, Ashcroft FM. Girard CA, et al. Among authors: ashcroft fm. Pflugers Arch. 2006 Dec;453(3):323-32. doi: 10.1007/s00424-006-0112-3. Epub 2006 Sep 22. Pflugers Arch. 2006. PMID: 17021801

6

Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress.

Freeman H, Shimomura K, Cox RD, Ashcroft FM. Freeman H, et al. Among authors: ashcroft fm. Biochem Soc Trans. 2006 Nov;34(Pt 5):806-10. doi: 10.1042/BST0340806. Biochem Soc Trans. 2006. PMID: 17052203

7

R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion.

Zhang Q, Bengtsson M, Partridge C, Salehi A, Braun M, Cox R, Eliasson L, Johnson PR, Renström E, Schneider T, Berggren PO, Göpel S, Ashcroft FM, Rorsman P. Zhang Q, et al. Among authors: ashcroft fm. Nat Cell Biol. 2007 Apr;9(4):453-60. doi: 10.1038/ncb1563. Epub 2007 Mar 18. Nat Cell Biol. 2007. PMID: 17369816

8

Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane.

Olofsson CS, Collins S, Bengtsson M, Eliasson L, Salehi A, Shimomura K, Tarasov A, Holm C, Ashcroft F, Rorsman P. Olofsson CS, et al. Diabetes. 2007 Jul;56(7):1888-97. doi: 10.2337/db06-1150. Epub 2007 Apr 24. Diabetes. 2007. PMID: 17456851 Free article.

9

PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.

Medina-Gomez G, Gray SL, Yetukuri L, Shimomura K, Virtue S, Campbell M, Curtis RK, Jimenez-Linan M, Blount M, Yeo GS, Lopez M, Seppänen-Laakso T, Ashcroft FM, Oresic M, Vidal-Puig A. Medina-Gomez G, et al. Among authors: ashcroft fm. PLoS Genet. 2007 Apr 27;3(4):e64. doi: 10.1371/journal.pgen.0030064. PLoS Genet. 2007. PMID: 17465682 Free PMC article.

10

Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.

Könner AC, Janoschek R, Plum L, Jordan SD, Rother E, Ma X, Xu C, Enriori P, Hampel B, Barsh GS, Kahn CR, Cowley MA, Ashcroft FM, Brüning JC. Könner AC, et al. Among authors: ashcroft fm. Cell Metab. 2007 Jun;5(6):438-49. doi: 10.1016/j.cmet.2007.05.004. Cell Metab. 2007. PMID: 17550779 Free article.

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