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Overlapping distribution of K(ATP) channel-forming Kir6.2 subunit and the sulfonylurea receptor SUR1 in rodent brain.
Karschin C, Ecke C, Ashcroft FM, Karschin A. Karschin C, et al. Among authors: ashcroft fm. FEBS Lett. 1997 Jan 13;401(1):59-64. doi: 10.1016/s0014-5793(96)01438-x. FEBS Lett. 1997. PMID: 9003806
Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles.
Fotinou C, Aittoniemi J, de Wet H, Polidori A, Pucci B, Sansom MS, VĂ©nien-Bryan C, Ashcroft FM. Fotinou C, et al. Among authors: ashcroft fm. FEBS J. 2013 Feb;280(4):1051-63. doi: 10.1111/febs.12097. Epub 2013 Jan 27. FEBS J. 2013. PMID: 23253866 Free PMC article.
The ATPase activities of sulfonylurea receptor 2A and sulfonylurea receptor 2B are influenced by the C-terminal 42 amino acids.
de Wet H, Fotinou C, Amad N, Dreger M, Ashcroft FM. de Wet H, et al. Among authors: ashcroft fm. FEBS J. 2010 Jun;277(12):2654-62. doi: 10.1111/j.1742-464X.2010.07675.x. FEBS J. 2010. PMID: 20553499 Free PMC article.
Mapping the architecture of the ATP-binding site of the KATP channel subunit Kir6.2.
Dabrowski M, Tarasov A, Ashcroft FM. Dabrowski M, et al. Among authors: ashcroft fm. J Physiol. 2004 Jun 1;557(Pt 2):347-54. doi: 10.1113/jphysiol.2003.059105. Epub 2004 Mar 5. J Physiol. 2004. PMID: 15004210 Free PMC article.
A universally conserved residue in the SUR1 subunit of the KATP channel is essential for translating nucleotide binding at SUR1 into channel opening.
de Wet H, Shimomura K, Aittoniemi J, Ahmad N, Lafond M, Sansom MS, Ashcroft FM. de Wet H, et al. Among authors: ashcroft fm. J Physiol. 2012 Oct 15;590(20):5025-36. doi: 10.1113/jphysiol.2012.236075. Epub 2012 Jul 16. J Physiol. 2012. PMID: 22802590 Free PMC article.
A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit.
Tammaro P, Ashcroft FM. Tammaro P, et al. Among authors: ashcroft fm. J Physiol. 2007 Nov 1;584(Pt 3):743-53. doi: 10.1113/jphysiol.2007.143149. Epub 2007 Sep 13. J Physiol. 2007. PMID: 17855752 Free PMC article.
Scavenging of 14-3-3 proteins reveals their involvement in the cell-surface transport of ATP-sensitive K+ channels.
Heusser K, Yuan H, Neagoe I, Tarasov AI, Ashcroft FM, Schwappach B. Heusser K, et al. Among authors: ashcroft fm. J Cell Sci. 2006 Oct 15;119(Pt 20):4353-63. doi: 10.1242/jcs.03196. J Cell Sci. 2006. PMID: 17038548
Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP) channels.
Hansen AM, Hansen JB, Carr RD, Ashcroft FM, Wahl P. Hansen AM, et al. Among authors: ashcroft fm. Br J Pharmacol. 2005 Feb;144(4):551-7. doi: 10.1038/sj.bjp.0706082. Br J Pharmacol. 2005. PMID: 15678092 Free PMC article.
Inhibition of ATP-sensitive potassium channels by haloperidol.
Yang SB, Proks P, Ashcroft FM, Rupnik M. Yang SB, et al. Among authors: ashcroft fm. Br J Pharmacol. 2004 Dec;143(8):960-7. doi: 10.1038/sj.bjp.0706017. Epub 2004 Nov 8. Br J Pharmacol. 2004. PMID: 15533888 Free PMC article.
Functional analysis of a structural model of the ATP-binding site of the KATP channel Kir6.2 subunit.
Antcliff JF, Haider S, Proks P, Sansom MS, Ashcroft FM. Antcliff JF, et al. Among authors: ashcroft fm. EMBO J. 2005 Jan 26;24(2):229-39. doi: 10.1038/sj.emboj.7600487. Epub 2005 Jan 13. EMBO J. 2005. PMID: 15650751 Free PMC article.
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