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5-HT inhibition of rat insulin 2 promoter Cre recombinase transgene and proopiomelanocortin neuron excitability in the mouse arcuate nucleus.
Hisadome K, Smith MA, Choudhury AI, Claret M, Withers DJ, Ashford ML. Hisadome K, et al. Neuroscience. 2009 Mar 3;159(1):83-93. doi: 10.1016/j.neuroscience.2008.12.003. Epub 2008 Dec 14. Neuroscience. 2009. PMID: 19135134 Free PMC article.
Oleate induces KATP channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge.
Dadak S, Beall C, Vlachaki Walker JM, Soutar MPM, McCrimmon RJ, Ashford MLJ. Dadak S, et al. Neuroscience. 2017 Mar 27;346:29-42. doi: 10.1016/j.neuroscience.2016.12.053. Epub 2017 Jan 9. Neuroscience. 2017. PMID: 28087336 Free PMC article.
Continuous hypothalamic K(ATP) activation blunts glucose counter-regulation in vivo in rats and suppresses K(ATP) conductance in vitro.
Beall C, Haythorne E, Fan X, Du Q, Jovanovic S, Sherwin RS, Ashford ML, McCrimmon RJ. Beall C, et al. Diabetologia. 2013 Sep;56(9):2088-92. doi: 10.1007/s00125-013-2970-5. Epub 2013 Jun 22. Diabetologia. 2013. PMID: 23793715
Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.
Beall C, Piipari K, Al-Qassab H, Smith MA, Parker N, Carling D, Viollet B, Withers DJ, Ashford ML. Beall C, et al. Biochem J. 2010 Jul 15;429(2):323-33. doi: 10.1042/BJ20100231. Biochem J. 2010. PMID: 20465544 Free PMC article.
Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances.
Smith MA, Hisadome K, Al-Qassab H, Heffron H, Withers DJ, Ashford ML. Smith MA, et al. J Physiol. 2007 Jan 15;578(Pt 2):425-38. doi: 10.1113/jphysiol.2006.119479. Epub 2006 Oct 26. J Physiol. 2007. PMID: 17068101 Free PMC article.
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