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Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use.
Patani H, Bunney TD, Thiyagarajan N, Norman RA, Ogg D, Breed J, Ashford P, Potterton A, Edwards M, Williams SV, Thomson GS, Pang CS, Knowles MA, Breeze AL, Orengo C, Phillips C, Katan M. Patani H, et al. Among authors: ashford p. Oncotarget. 2016 Apr 26;7(17):24252-68. doi: 10.18632/oncotarget.8132. Oncotarget. 2016. PMID: 26992226 Free PMC article.
Unique signalling connectivity of FGFR3-TACC3 oncoprotein revealed by quantitative phosphoproteomics and differential network analysis.
Lombardi B, Ashford P, Moya-Garcia AA, Rust A, Crawford M, Williams SV, Knowles MA, Katan M, Orengo C, Godovac-Zimmermann J. Lombardi B, et al. Among authors: ashford p. Oncotarget. 2017 Oct 25;8(61):102898-102911. doi: 10.18632/oncotarget.22048. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262532 Free PMC article.
CATH: comprehensive structural and functional annotations for genome sequences.
Sillitoe I, Lewis TE, Cuff A, Das S, Ashford P, Dawson NL, Furnham N, Laskowski RA, Lee D, Lees JG, Lehtinen S, Studer RA, Thornton J, Orengo CA. Sillitoe I, et al. Among authors: ashford p. Nucleic Acids Res. 2015 Jan;43(Database issue):D376-81. doi: 10.1093/nar/gku947. Epub 2014 Oct 27. Nucleic Acids Res. 2015. PMID: 25348408 Free PMC article.
Gene3D: expanding the utility of domain assignments.
Lam SD, Dawson NL, Das S, Sillitoe I, Ashford P, Lee D, Lehtinen S, Orengo CA, Lees JG. Lam SD, et al. Among authors: ashford p. Nucleic Acids Res. 2016 Jan 4;44(D1):D404-9. doi: 10.1093/nar/gkv1231. Epub 2015 Nov 17. Nucleic Acids Res. 2016. PMID: 26578585 Free PMC article.
CATH: expanding the horizons of structure-based functional annotations for genome sequences.
Sillitoe I, Dawson N, Lewis TE, Das S, Lees JG, Ashford P, Tolulope A, Scholes HM, Senatorov I, Bujan A, Ceballos Rodriguez-Conde F, Dowling B, Thornton J, Orengo CA. Sillitoe I, et al. Among authors: ashford p. Nucleic Acids Res. 2019 Jan 8;47(D1):D280-D284. doi: 10.1093/nar/gky1097. Nucleic Acids Res. 2019. PMID: 30398663 Free PMC article.
SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals.
Lam SD, Bordin N, Waman VP, Scholes HM, Ashford P, Sen N, van Dorp L, Rauer C, Dawson NL, Pang CSM, Abbasian M, Sillitoe I, Edwards SJL, Fraternali F, Lees JG, Santini JM, Orengo CA. Lam SD, et al. Among authors: ashford p. Sci Rep. 2020 Oct 5;10(1):16471. doi: 10.1038/s41598-020-71936-5. Sci Rep. 2020. PMID: 33020502 Free PMC article.
CATH: increased structural coverage of functional space.
Sillitoe I, Bordin N, Dawson N, Waman VP, Ashford P, Scholes HM, Pang CSM, Woodridge L, Rauer C, Sen N, Abbasian M, Le Cornu S, Lam SD, Berka K, Varekova IH, Svobodova R, Lees J, Orengo CA. Sillitoe I, et al. Among authors: ashford p. Nucleic Acids Res. 2021 Jan 8;49(D1):D266-D273. doi: 10.1093/nar/gkaa1079. Nucleic Acids Res. 2021. PMID: 33237325 Free PMC article.
71 results