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Page 1
Mucosal Vaccination with a Self-Adjuvanted Lipopeptide Is Immunogenic and Protective against Mycobacterium tuberculosis.
Ashhurst AS, McDonald DM, Hanna CC, Stanojevic VA, Britton WJ, Payne RJ. Ashhurst AS, et al. J Med Chem. 2019 Sep 12;62(17):8080-8089. doi: 10.1021/acs.jmedchem.9b00832. Epub 2019 Aug 16. J Med Chem. 2019. PMID: 31373811
Total Synthesis of Glycosylated Human Interferon-γ.
Wang X, Ashhurst AS, Dowman LJ, Watson EE, Li HY, Fairbanks AJ, Larance M, Kwan A, Payne RJ. Wang X, et al. Among authors: ashhurst as. Org Lett. 2020 Sep 4;22(17):6863-6867. doi: 10.1021/acs.orglett.0c02401. Epub 2020 Aug 24. Org Lett. 2020. PMID: 32830985
Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L.
Ashhurst AS, Tang AH, Fajtová P, Yoon M, Aggarwal A, Stoye A, Larance M, Beretta L, Drelich A, Skinner D, Li L, Meek TD, McKerrow JH, Hook V, Tseng CK, Turville S, Gerwick WH, O'Donoghue AJ, Payne RJ. Ashhurst AS, et al. bioRxiv. 2020 Dec 24:2020.12.23.424111. doi: 10.1101/2020.12.23.424111. Preprint. bioRxiv. 2020. PMID: 33398273 Free PMC article.
Synthetic protein conjugate vaccines provide protection against Mycobacterium tuberculosis in mice.
Hanna CC, Ashhurst AS, Quan D, Maxwell JWC, Britton WJ, Payne RJ. Hanna CC, et al. Among authors: ashhurst as. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2013730118. doi: 10.1073/pnas.2013730118. Proc Natl Acad Sci U S A. 2021. PMID: 33468674 Free article.
CXCR6-Deficiency Improves the Control of Pulmonary Mycobacterium tuberculosis and Influenza Infection Independent of T-Lymphocyte Recruitment to the Lungs.
Ashhurst AS, Flórido M, Lin LCW, Quan D, Armitage E, Stifter SA, Stambas J, Britton WJ. Ashhurst AS, et al. Front Immunol. 2019 Mar 7;10:339. doi: 10.3389/fimmu.2019.00339. eCollection 2019. Front Immunol. 2019. PMID: 30899256 Free PMC article.
Synthesis of a Self-Adjuvanting MUC1 Vaccine via Diselenide-Selenoester Ligation-Deselenization.
McDonald DM, Hanna CC, Ashhurst AS, Corcilius L, Byrne SN, Payne RJ. McDonald DM, et al. Among authors: ashhurst as. ACS Chem Biol. 2018 Dec 21;13(12):3279-3285. doi: 10.1021/acschembio.8b00675. Epub 2018 Nov 14. ACS Chem Biol. 2018. PMID: 30359529
PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection.
Ashhurst AS, Parumasivam T, Chan JGY, Lin LCW, Flórido M, West NP, Chan HK, Britton WJ. Ashhurst AS, et al. PLoS One. 2018 Mar 19;13(3):e0194620. doi: 10.1371/journal.pone.0194620. eCollection 2018. PLoS One. 2018. PMID: 29554138 Free PMC article.
Inhalation of Respirable Crystalline Rifapentine Particles Induces Pulmonary Inflammation.
Parumasivam T, Ashhurst AS, Nagalingam G, Britton WJ, Chan HK. Parumasivam T, et al. Among authors: ashhurst as. Mol Pharm. 2017 Jan 3;14(1):328-335. doi: 10.1021/acs.molpharmaceut.6b00905. Epub 2016 Dec 15. Mol Pharm. 2017. PMID: 27977216