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Apoptosis control by death and decoy receptors.
Ashkenazi A, Dixit VM. Ashkenazi A, et al. Curr Opin Cell Biol. 1999 Apr;11(2):255-60. doi: 10.1016/s0955-0674(99)80034-9. Curr Opin Cell Biol. 1999. PMID: 10209153 Review.
Designer proteins to trigger cell death.
Fairbrother WJ, Ashkenazi A. Fairbrother WJ, et al. Among authors: ashkenazi a. Cell. 2014 Jun 19;157(7):1506-8. doi: 10.1016/j.cell.2014.06.010. Cell. 2014. PMID: 24949963
Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake.
Shang Y, Mao Y, Batson J, Scales SJ, Phillips G, Lackner MR, Totpal K, Williams S, Yang J, Tang Z, Modrusan Z, Tan C, Liang WC, Tsai SP, Vanderbilt A, Kozuka K, Hoeflich K, Tien J, Ross S, Li C, Lee SH, Song A, Wu Y, Stephan JP, Ashkenazi A, Zha J. Shang Y, et al. Among authors: ashkenazi a. Mol Cancer Ther. 2008 Sep;7(9):2599-608. doi: 10.1158/1535-7163.MCT-07-2401. Mol Cancer Ther. 2008. PMID: 18790743
Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models.
French DM, Lin BC, Wang M, Adams C, Shek T, Hötzel K, Bolon B, Ferrando R, Blackmore C, Schroeder K, Rodriguez LA, Hristopoulos M, Venook R, Ashkenazi A, Desnoyers LR. French DM, et al. Among authors: ashkenazi a. PLoS One. 2012;7(5):e36713. doi: 10.1371/journal.pone.0036713. Epub 2012 May 15. PLoS One. 2012. PMID: 22615798 Free PMC article.
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