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Adeno-associated viral gene therapy corrects a mouse model of argininosuccinic aciduria.
Mol Genet Metab. 2018 Nov;125(3):241-250. doi: 10.1016/j.ymgme.2018.08.013. Epub 2018 Aug 28.
Mol Genet Metab. 2018.
PMID: 30253962
CpG-depleted adeno-associated virus vectors evade immune detection.
Faust SM, Bell P, Cutler BJ, Ashley SN, Zhu Y, Rabinowitz JE, Wilson JM.
Faust SM, et al. Among authors: ashley sn.
J Clin Invest. 2013 Jul;123(7):2994-3001. doi: 10.1172/JCI68205. Epub 2013 Jun 17.
J Clin Invest. 2013.
PMID: 23778142
Free PMC article.
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Alternative Start Sites Downstream of Non-Sense Mutations Drive Antigen Presentation and Tolerance Induction to C-Terminal Epitopes.
Ashley SN, Somanathan S, Hinderer C, Arias M, McMenamin D, Draper C, Wilson JM.
Ashley SN, et al.
J Immunol. 2017 Jun 15;198(12):4581-4587. doi: 10.4049/jimmunol.1601131. Epub 2017 May 12.
J Immunol. 2017.
PMID: 28500077
Free PMC article.
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A Gene Therapy Approach to Improve Copper Metabolism and Prevent Liver Damage in a Mouse Model of Wilson Disease.
Greig JA, Nordin JML, Smith MK, Ashley SN, Draper C, Zhu Y, Bell P, Buza EL, Wilson JM.
Greig JA, et al. Among authors: ashley sn.
Hum Gene Ther Clin Dev. 2019 Mar;30(1):29-39. doi: 10.1089/humc.2018.219. Epub 2019 Feb 25.
Hum Gene Ther Clin Dev. 2019.
PMID: 30693797
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TLR9 signaling mediates adaptive immunity following systemic AAV gene therapy.
Ashley SN, Somanathan S, Giles AR, Wilson JM.
Ashley SN, et al.
Cell Immunol. 2019 Dec;346:103997. doi: 10.1016/j.cellimm.2019.103997. Epub 2019 Oct 26.
Cell Immunol. 2019.
PMID: 31703913
Free PMC article.
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Muscle-directed AAV gene therapy rescues the maple syrup urine disease phenotype in a mouse model.
Greig JA, Jennis M, Dandekar A, Chorazeczewski JK, Smith MK, Ashley SN, Yan H, Wilson JM.
Greig JA, et al. Among authors: ashley sn.
Mol Genet Metab. 2021 Sep-Oct;134(1-2):139-146. doi: 10.1016/j.ymgme.2021.08.003. Epub 2021 Aug 17.
Mol Genet Metab. 2021.
PMID: 34454844
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Treating Transthyretin Amyloidosis via Adeno-Associated Virus Vector Delivery of Meganucleases.
Greig JA, Breton C, Ashley SN, Martins KM, Gorsuch C, Chorazeczewski JK, Furmanak T, Smith MK, Zhu Y, Bell P, Shoop W, Li H, Smith J, Tomberlin G, Clark P, Mitchell TW, Buza EL, Yan H, Jantz D, Wilson JM.
Greig JA, et al. Among authors: ashley sn.
Hum Gene Ther. 2022 Nov;33(21-22):1174-1186. doi: 10.1089/hum.2022.061.
Hum Gene Ther. 2022.
PMID: 36375122
Free PMC article.
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