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Aging circadian rhythms and cannabinoids.
Hodges EL, Ashpole NM. Hodges EL, et al. Among authors: ashpole nm. Neurobiol Aging. 2019 Jul;79:110-118. doi: 10.1016/j.neurobiolaging.2019.03.008. Epub 2019 Mar 25. Neurobiol Aging. 2019. PMID: 31035036 Free PMC article. Review.
Novel choline analog 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol produces sympathoinhibition, hypotension, and antihypertensive effects.
Menegatti R, Carvalho FS, Lião LM, Villavicencio B, Verli H, Mourão AA, Xavier CH, Castro CH, Pedrino GR, Franco OL, Oliveira-Silva I, Ashpole NM, Silva ON, Costa EA, Fajemiroye JO. Menegatti R, et al. Among authors: ashpole nm. Naunyn Schmiedebergs Arch Pharmacol. 2019 Sep;392(9):1071-1083. doi: 10.1007/s00210-019-01649-8. Epub 2019 May 2. Naunyn Schmiedebergs Arch Pharmacol. 2019. PMID: 31049606
Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
Tarantini S, Tucsek Z, Valcarcel-Ares MN, Toth P, Gautam T, Giles CB, Ballabh P, Wei JY, Wren JD, Ashpole NM, Sonntag WE, Ungvari Z, Csiszar A. Tarantini S, et al. Among authors: ashpole nm. Age (Dordr). 2016 Aug;38(4):273-289. doi: 10.1007/s11357-016-9931-0. Epub 2016 Sep 9. Age (Dordr). 2016. PMID: 27613724 Free PMC article.
IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.
Tarantini S, Giles CB, Wren JD, Ashpole NM, Valcarcel-Ares MN, Wei JY, Sonntag WE, Ungvari Z, Csiszar A. Tarantini S, et al. Among authors: ashpole nm. Age (Dordr). 2016 Aug;38(4):239-258. doi: 10.1007/s11357-016-9943-9. Epub 2016 Aug 26. Age (Dordr). 2016. PMID: 27566308 Free PMC article.
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