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Inherited cardiomyopathies.
Watkins H, Ashrafian H, Redwood C. Watkins H, et al. N Engl J Med. 2011 Apr 28;364(17):1643-56. doi: 10.1056/NEJMra0902923. N Engl J Med. 2011. PMID: 21524215 Review. No abstract available.
No Evidence of Myocardial Oxygen Deprivation in Nonischemic Heart Failure.
Dass S, Holloway CJ, Cochlin LE, Rider OJ, Mahmod M, Robson M, Sever E, Clarke K, Watkins H, Ashrafian H, Karamitsos TD, Neubauer S. Dass S, et al. Circ Heart Fail. 2015 Nov;8(6):1088-93. doi: 10.1161/CIRCHEARTFAILURE.114.002169. Epub 2015 Sep 2. Circ Heart Fail. 2015. PMID: 26333351 Free PMC article.
Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion.
Ashrafian H, Redwood C, Blair E, Watkins H. Ashrafian H, et al. Trends Genet. 2003 May;19(5):263-8. doi: 10.1016/S0168-9525(03)00081-7. Trends Genet. 2003. PMID: 12711218 Review.
Targets for therapy in sarcomeric cardiomyopathies.
Tardiff JC, Carrier L, Bers DM, Poggesi C, Ferrantini C, Coppini R, Maier LS, Ashrafian H, Huke S, van der Velden J. Tardiff JC, et al. Cardiovasc Res. 2015 Apr 1;105(4):457-70. doi: 10.1093/cvr/cvv023. Epub 2015 Jan 29. Cardiovasc Res. 2015. PMID: 25634554 Free PMC article. Review.
Genetic cardiomyopathies causing heart failure.
Cahill TJ, Ashrafian H, Watkins H. Cahill TJ, et al. Circ Res. 2013 Aug 30;113(6):660-75. doi: 10.1161/CIRCRESAHA.113.300282. Circ Res. 2013. PMID: 23989711 Review.
Disease pathways and novel therapeutic targets in hypertrophic cardiomyopathy.
Ashrafian H, McKenna WJ, Watkins H. Ashrafian H, et al. Circ Res. 2011 Jun 24;109(1):86-96. doi: 10.1161/CIRCRESAHA.111.242974. Circ Res. 2011. PMID: 21700950 Review.
Reviews of translational medicine and genomics in cardiovascular disease: new disease taxonomy and therapeutic implications cardiomyopathies: therapeutics based on molecular phenotype.
Ashrafian H, Watkins H. Ashrafian H, et al. J Am Coll Cardiol. 2007 Mar 27;49(12):1251-64. doi: 10.1016/j.jacc.2006.10.073. Epub 2007 Mar 9. J Am Coll Cardiol. 2007. PMID: 17394955 Review.
The pathophysiology of heart failure: a tale of two old paradigms revisited.
Ashrafian H, Williams L, Frenneaux MP. Ashrafian H, et al. Clin Med (Lond). 2008 Apr;8(2):192-7. doi: 10.7861/clinmedicine.8-2-192. Clin Med (Lond). 2008. PMID: 18478870 Free PMC article.
Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy.
Gehmlich K, Dodd MS, Allwood JW, Kelly M, Bellahcene M, Lad HV, Stockenhuber A, Hooper C, Ashrafian H, Redwood CS, Carrier L, Dunn WB. Gehmlich K, et al. Mol Biosyst. 2015 Feb;11(2):564-73. doi: 10.1039/c4mb00594e. Mol Biosyst. 2015. PMID: 25437646
A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy.
Ashrafian H, Docherty L, Leo V, Towlson C, Neilan M, Steeples V, Lygate CA, Hough T, Townsend S, Williams D, Wells S, Norris D, Glyn-Jones S, Land J, Barbaric I, Lalanne Z, Denny P, Szumska D, Bhattacharya S, Griffin JL, Hargreaves I, Fernandez-Fuentes N, Cheeseman M, Watkins H, Dear TN. Ashrafian H, et al. PLoS Genet. 2010 Jun 24;6(6):e1001000. doi: 10.1371/journal.pgen.1001000. PLoS Genet. 2010. PMID: 20585624 Free PMC article.
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