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A new selective pharmacological enhancer of the Orai1 Ca2+ channel reveals roles for Orai1 in smooth and skeletal muscle functions.
Azimi I, Stevenson RJ, Zhang X, Meizoso-Huesca A, Xin P, Johnson M, Flanagan JU, Chalmers SB, Yoast RE, Kapure JS, Ross BP, Vetter I, Ashton MR, Launikonis BS, Denny WA, Trebak M, Monteith GR. Azimi I, et al. Among authors: ashton mr. ACS Pharmacol Transl Sci. 2020 Feb 14;3(1):135-147. doi: 10.1021/acsptsci.9b00081. Epub 2020 Jan 13. ACS Pharmacol Transl Sci. 2020. PMID: 32190822 Free PMC article.
Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.
Armer RE, Ashton MR, Boyd EA, Brennan CJ, Brookfield FA, Gazi L, Gyles SL, Hay PA, Hunter MG, Middlemiss D, Whittaker M, Xue L, Pettipher R. Armer RE, et al. Among authors: ashton mr. J Med Chem. 2005 Oct 6;48(20):6174-7. doi: 10.1021/jm050519b. J Med Chem. 2005. PMID: 16190744
"Blind" bronchoalveolar lavage.
Ashton MR. Ashton MR. Lancet. 1992 Oct 31;340(8827):1104. doi: 10.1016/0140-6736(92)93132-7. Lancet. 1992. PMID: 1357499 No abstract available.
Turnover of exogenous artificial surfactant.
Ashton MR, Postle AD, Hall MA, Austin NC, Smith DE, Normand IC. Ashton MR, et al. Arch Dis Child. 1992 Apr;67(4 Spec No):383-7. doi: 10.1136/adc.67.4_spec_no.383. Arch Dis Child. 1992. PMID: 1586175 Free PMC article. Clinical Trial.
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