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Rare variant association analysis methods for complex traits.
Asimit J, Zeggini E. Asimit J, et al. Annu Rev Genet. 2010;44:293-308. doi: 10.1146/annurev-genet-102209-163421. Annu Rev Genet. 2010. PMID: 21047260 Review.
Gene- or region-based analysis of genome-wide association studies.
Beyene J, Tritchler D, Asimit JL, Hamid JS. Beyene J, et al. Among authors: asimit jl. Genet Epidemiol. 2009;33 Suppl 1(Suppl 1):S105-10. doi: 10.1002/gepi.20481. Genet Epidemiol. 2009. PMID: 19924708 Free PMC article.
Genome-wide association analysis of imputed rare variants: application to seven common complex diseases.
Mägi R, Asimit JL, Day-Williams AG, Zeggini E, Morris AP. Mägi R, et al. Among authors: asimit jl. Genet Epidemiol. 2012 Dec;36(8):785-96. doi: 10.1002/gepi.21675. Epub 2012 Sep 5. Genet Epidemiol. 2012. PMID: 22951892 Free PMC article.
Imputation of rare variants in next-generation association studies.
Asimit JL, Zeggini E. Asimit JL, et al. Hum Hered. 2012;74(3-4):196-204. doi: 10.1159/000345602. Epub 2013 Apr 11. Hum Hered. 2012. PMID: 23594497 Free PMC article.
Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.
Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, Choi S, Chen H, Kaur I, Takeuchi F, Fontanillas P, Thuillier D, Yengo L, Below JE, Tam CH, Wu Y, Abecasis G, Altshuler D, Bell GI, Blangero J, Burtt NP, Duggirala R, Florez JC, Hanis CL, Seielstad M, Atzmon G, Chan JC, Ma RC, Froguel P, Wilson JG, Bharadwaj D, Dupuis J, Meigs JB, Cho YS, Park T, Kooner JS, Chambers JC, Saleheen D, Kadowaki T, Tai ES, Mohlke KL, Cox NJ, Ferrer J, Zeggini E, Kato N, Teo YY, Boehnke M, McCarthy MI, Morris AP; T2D-GENES Consortium. Horikoshi M, et al. Among authors: asimit jl. Hum Mol Genet. 2016 May 15;25(10):2070-2081. doi: 10.1093/hmg/ddw048. Epub 2016 Feb 23. Hum Mol Genet. 2016. PMID: 26911676 Free PMC article.
Trans-ethnic study design approaches for fine-mapping.
Asimit JL, Hatzikotoulas K, McCarthy M, Morris AP, Zeggini E. Asimit JL, et al. Eur J Hum Genet. 2016 Aug;24(9):1330-6. doi: 10.1038/ejhg.2016.1. Epub 2016 Feb 3. Eur J Hum Genet. 2016. PMID: 26839038 Free PMC article.
A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits.
Asimit JL, Panoutsopoulou K, Wheeler E, Berndt SI; GIANT consortium, the arcOGEN consortium, Cordell HJ, Morris AP, Zeggini E, Barroso I. Asimit JL, et al. Genet Epidemiol. 2015 Dec;39(8):624-34. doi: 10.1002/gepi.21919. Epub 2015 Sep 28. Genet Epidemiol. 2015. PMID: 26411566 Free PMC article.
ARIEL and AMELIA: testing for an accumulation of rare variants using next-generation sequencing data.
Asimit JL, Day-Williams AG, Morris AP, Zeggini E. Asimit JL, et al. Hum Hered. 2012;73(2):84-94. doi: 10.1159/000336982. Epub 2012 Mar 22. Hum Hered. 2012. PMID: 22441326 Free PMC article.
A two-stage inter-rater approach for enrichment testing of variants associated with multiple traits.
Asimit JL, Payne F, Morris AP, Cordell HJ, Barroso I. Asimit JL, et al. Eur J Hum Genet. 2017 Feb;25(3):341-349. doi: 10.1038/ejhg.2016.171. Epub 2016 Dec 21. Eur J Hum Genet. 2017. PMID: 28000695 Free PMC article.
An evaluation of different meta-analysis approaches in the presence of allelic heterogeneity.
Asimit J, Day-Williams A, Zgaga L, Rudan I, Boraska V, Zeggini E. Asimit J, et al. Eur J Hum Genet. 2012 Jun;20(6):709-12. doi: 10.1038/ejhg.2011.274. Epub 2012 Feb 1. Eur J Hum Genet. 2012. PMID: 22293689 Free PMC article.
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