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7-Chloro-5-(4-hydroxyphenyl)-1-methyl-3-(naphthalen-2-ylmethyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one (Bz-423), a benzodiazepine, suppresses keratinocyte proliferation and has antipsoriatic activity in the human skin-severe, combined immunodeficient mouse transplant model.
Bhagavathula N, Nerusu KC, Hanosh A, Aslam MN, Sundberg TB, Opipari AW Jr, Johnson K, Kang S, Glick GD, Varani J. Bhagavathula N, et al. Among authors: aslam mn. J Pharmacol Exp Ther. 2008 Mar;324(3):938-47. doi: 10.1124/jpet.107.130955. Epub 2007 Nov 30. J Pharmacol Exp Ther. 2008. PMID: 18055879
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