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Circulating microRNAs in patients with non-alcoholic fatty liver disease.
Celikbilek M, Baskol M, Taheri S, Deniz K, Dogan S, Zararsiz G, Gursoy S, Guven K, Ozbakır O, Dundar M, Yucesoy M. Celikbilek M, et al. World J Hepatol. 2014 Aug 27;6(8):613-20. doi: 10.4254/wjh.v6.i8.613. World J Hepatol. 2014. PMID: 25232454 Free PMC article.
All NAFLD cases were scored using the NAFLD activity score. The relative expressions of miR-197, miR-146b, miR-10b, miR-181d, miR-34a, miR-122, miR-99a and miR-29a were analyzed using real-time polymerase chain reaction. RES …
All NAFLD cases were scored using the NAFLD activity score. The relative expressions of miR-197, miR-146b, miR-10b, …
High-throughput sequencing approach uncovers the miRNome of peritoneal endometriotic lesions and adjacent healthy tissues.
Saare M, Rekker K, Laisk-Podar T, Sõritsa D, Roost AM, Simm J, Velthut-Meikas A, Samuel K, Metsalu T, Karro H, Sõritsa A, Salumets A, Peters M. Saare M, et al. PLoS One. 2014 Nov 11;9(11):e112630. doi: 10.1371/journal.pone.0112630. eCollection 2014. PLoS One. 2014. PMID: 25386850 Free PMC article.
We found five miRNAs specific to epithelial cells--miR-34c, miR-449a, miR-200a, miR-200b and miR-141 showing significantly higher expression in peritoneal endometriotic lesions compared to healthy peritoneal tissues. We also determined the expre …
We found five miRNAs specific to epithelial cells--miR-34c, miR-449a, miR-200a, miR-200b and miR-141 show …
Differentially-Expressed miRNAs in Ectopic Stromal Cells Contribute to Endometriosis Development: The Plausible Role of miR-139-5p and miR-375.
Rekker K, Tasa T, Saare M, Samuel K, Kadastik Ü, Karro H, Götte M, Salumets A, Peters M. Rekker K, et al. Int J Mol Sci. 2018 Nov 28;19(12):3789. doi: 10.3390/ijms19123789. Int J Mol Sci. 2018. PMID: 30487429 Free PMC article.
The analysis revealed 149 abnormally expressed miRNAs in endometriotic lesions, including extensive upregulation of miR-139-5p and downregulation of miR-375 compared to eutopic cells. miRNA transfection experiments in the endometrial stromal cell line ST-T1b showed …
The analysis revealed 149 abnormally expressed miRNAs in endometriotic lesions, including extensive upregulation of miR-139-5p and do …
Comparison of serum exosome isolation methods for microRNA profiling.
Rekker K, Saare M, Roost AM, Kubo AL, Zarovni N, Chiesi A, Salumets A, Peters M. Rekker K, et al. Clin Biochem. 2014 Jan;47(1-2):135-8. doi: 10.1016/j.clinbiochem.2013.10.020. Epub 2013 Oct 29. Clin Biochem. 2014. PMID: 24183884
RESULTS: Although a strong correlation of exosomal miRNA profiles was observed between the two isolation methods, distinct clusters of miRNA levels between the used methods were identified. The detected levels of two miRNAs, miR-92a and miR-486-5p, were significantl …
RESULTS: Although a strong correlation of exosomal miRNA profiles was observed between the two isolation methods, distinct clusters of miRNA …
A Two-Cohort RNA-seq Study Reveals Changes in Endometrial and Blood miRNome in Fertile and Infertile Women.
Rekker K, Altmäe S, Suhorutshenko M, Peters M, Martinez-Blanch JF, Codoñer FM, Vilella F, Simón C, Salumets A, Velthut-Meikas A. Rekker K, et al. Genes (Basel). 2018 Nov 23;9(12):574. doi: 10.3390/genes9120574. Genes (Basel). 2018. PMID: 30477193 Free PMC article.
Besides novel findings, we confirmed the involvement of miR-30 and miR-200 family members in mid-secretory endometrial functions....
Besides novel findings, we confirmed the involvement of miR-30 and miR-200 family members in mid-secretory endometrial functio …