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Tissue tumor marker expression in smokers, including serum cotinine concentrations, in women with cervical intraepithelial neoplasia or normal squamous cervical epithelium.
Samir R, Asplund A, Tot T, Pekar G, Hellberg D. Samir R, et al. Am J Obstet Gynecol. 2010 Jun;202(6):579.e1-7. doi: 10.1016/j.ajog.2009.11.034. Epub 2010 Jan 13. Am J Obstet Gynecol. 2010. PMID: 20060094
This provides biologic evidence of smoking being a true cofactor in cervical neoplasia....
This provides biologic evidence of smoking being a true cofactor in cervical neoplasia....
High-risk HPV infection and CIN grade correlates to the expression of c-myc, CD4+, FHIT, E-cadherin, Ki-67, and p16INK4a.
Samir R, Asplund A, Tot T, Pekar G, Hellberg D. Samir R, et al. J Low Genit Tract Dis. 2011 Oct;15(4):280-6. doi: 10.1097/LGT.0b013e318215170c. J Low Genit Tract Dis. 2011. PMID: 21558960
OBJECTIVE: : This study aimed to investigate correlations between a panel of biomarkers/tumor markers and high-risk (HR) human papillomavirus (HPV)-positive versus HR-HPV-negative cervical lesions. MATERIALS AND METHODS: : The study included 188 women who consecutively att …
OBJECTIVE: : This study aimed to investigate correlations between a panel of biomarkers/tumor markers and high-risk (HR) human papill …
Molecular profiling using tissue microarrays as a tool to identify predictive biomarkers in laryngeal cancer treated with radiotherapy.
Holgersson G, Ekman S, Reizenstein J, Bergqvist M, Pontén F, Uhlén M, Magnusson K, Jonnalagadda P, Asplund A, Strömberg S, Linder A, Blomquist E, Liljeholm M, Lödén B, Hellström K, Bergström S. Holgersson G, et al. Cancer Genomics Proteomics. 2010 Jan-Feb;7(1):1-7. Cancer Genomics Proteomics. 2010. PMID: 20181625
RESULTS: A total of 39 patients were included in the present study. Nuclear MSH2 staining was statistically significantly correlated to Ki-67 expression (p=0.022). ...However, with larger patient cohorts, we believe that protein profiling using TMAs and immunohistochemistr …
RESULTS: A total of 39 patients were included in the present study. Nuclear MSH2 staining was statistically significantly correlated …
Oral contraceptive and progestin-only use correlates to tissue tumor marker expression in women with cervical intraepithelial neoplasia.
Samir R, Asplund A, Tot T, Pekar G, Hellberg D. Samir R, et al. Contraception. 2012 Mar;85(3):288-93. doi: 10.1016/j.contraception.2011.09.001. Epub 2011 Oct 11. Contraception. 2012. PMID: 22067748
When users of progestogen-only contraceptives were analyzed, there was a lower expression of cytokeratin 10 and interleukin 10. When only MID users were analyzed, a high expression of p53 was found. Expression of Cox-2, p53 and retinoblastoma protein differed betwee …
When users of progestogen-only contraceptives were analyzed, there was a lower expression of cytokeratin 10 and interleukin 10. When …
Socioeconomic characteristics, housing conditions and criminal offences among women with cervical neoplasia.
Billström E, Sundström-Poromaa I, Stålberg K, Asplund A, Hellberg D. Billström E, et al. Acta Obstet Gynecol Scand. 2013 Aug;92(8):888-94. doi: 10.1111/aogs.12151. Epub 2013 May 10. Acta Obstet Gynecol Scand. 2013. PMID: 23590762
RESULTS: Women with cervical neoplasia had a lower socioeconomic status and a lower educational level than their age-matched controls. ...CONCLUSIONS: The results indicate that women with cervical neoplasia belong to a socioeconomically disadvantaged group. F …
RESULTS: Women with cervical neoplasia had a lower socioeconomic status and a lower educational level than their age-matched c …
Analysis of intratumoral heterogeneity of chromosome 3p deletions and genetic evidence of polyclonal origin of cervical squamous carcinoma.
Guo Z, Wu F, Asplund A, Hu X, Mazurenko N, Kisseljov F, Pontén J, Wilander E. Guo Z, et al. Mod Pathol. 2001 Feb;14(2):54-61. doi: 10.1038/modpathol.3880256. Mod Pathol. 2001. PMID: 11235906
Correlation between LRIG1 and LRIG2 expressions and expression of 11 tumor markers, with special reference to tumor suppressors, in CIN and normal cervical epithelium.
Lindström AK, Asplund A, Hellberg D. Lindström AK, et al. Gynecol Oncol. 2011 Aug;122(2):372-6. doi: 10.1016/j.ygyno.2011.04.049. Epub 2011 May 31. Gynecol Oncol. 2011. PMID: 21632100
The role of p53 codon 72 and human papilloma virus status of cutaneous squamous cell carcinoma in the Swedish population.
Gustafsson AC, Ren ZP, Asplund A, Pontén F, Lundeberg J. Gustafsson AC, et al. Acta Derm Venereol. 2004;84(6):439-44. doi: 10.1080/00015550410021673. Acta Derm Venereol. 2004. PMID: 15844633
Data also indicate that anogenital HPV is more common in tumour samples, but HPV infection was not identified as a significant risk factor for developing SCC. The presence of anogenital HPV, but not EV HPV might be a risk factor for development of cutaneous SCC....
Data also indicate that anogenital HPV is more common in tumour samples, but HPV infection was not identified as a significant risk f …
Affinity proteomics for systematic protein profiling of chromosome 21 gene products in human tissues.
Agaton C, Galli J, Höidén Guthenberg I, Janzon L, Hansson M, Asplund A, Brundell E, Lindberg S, Ruthberg I, Wester K, Wurtz D, Höög C, Lundeberg J, Ståhl S, Pontén F, Uhlén M. Agaton C, et al. Mol Cell Proteomics. 2003 Jun;2(6):405-14. doi: 10.1074/mcp.M300022-MCP200. Epub 2003 Jun 9. Mol Cell Proteomics. 2003. PMID: 12796447
Using human tissue arrays, a systematic profiling of protein expression and subcellular localization was undertaken for the putative gene products. The results suggest that this affinity proteomics strategy can be used to produce a proteome atlas, describing distrib …
Using human tissue arrays, a systematic profiling of protein expression and subcellular localization was undertaken for the putative …
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