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Assessment of the U937 cell line for the detection of contact allergens.
Python F, Goebel C, Aeby P. Python F, et al. Toxicol Appl Pharmacol. 2007 Apr 15;220(2):113-24. doi: 10.1016/j.taap.2006.12.026. Epub 2007 Jan 3. Toxicol Appl Pharmacol. 2007. PMID: 17306317
The human myeloid cell line U937 was evaluated as an in vitro test system to identify contact sensitizers in order to develop alternatives to animal tests for the cosmetic industry. ...Test item-specific modulations of the chosen activation markers (CD …
The human myeloid cell line U937 was evaluated as an in vitro test system to identify contact sensitizers in ord …
Evaluation of in vitro testing strategies for hazard assessment of the skin sensitization potential of "real-life" mixtures: The case of henna-based hair-colouring products containing p-phenylenediamine.
de Ávila RI, Veloso DFMC, Teixeira GC, Rodrigues TL, Lindberg T, Lindstedt M, Fonseca SG, Lima EM, Valadares MC. de Ávila RI, et al. Contact Dermatitis. 2019 Sep;81(3):194-209. doi: 10.1111/cod.13294. Epub 2019 Jun 20. Contact Dermatitis. 2019. PMID: 31006869
BACKGROUND: Allergic contact dermatitis caused by henna-based hair-colouring products has been associated with adulteration of henna with p-phenylenediamine (PPD). OBJECTIVES: To develop a testing approach based on in vitro techniques that address key events within the ski …
BACKGROUND: Allergic contact dermatitis caused by henna-based hair-colouring products has been associated with adulteration of henna …
Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals.
Bauch C, Kolle SN, Fabian E, Pachel C, Ramirez T, Wiench B, Wruck CJ, van Ravenzwaay B, Landsiedel R. Bauch C, et al. Toxicol In Vitro. 2011 Sep;25(6):1162-8. doi: 10.1016/j.tiv.2011.05.030. Epub 2011 Jun 7. Toxicol In Vitro. 2011. PMID: 21669280
Allergic contact dermatitis is induced by repeated skin contact with an allergen. ...Currently, we performed intralaboratory validations of four assays addressing three different events during induction of skin sensitization. (1) The Direct Peptide Reactivity …
Allergic contact dermatitis is induced by repeated skin contact with an allergen. ...Currently, we performed intralabor …