Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span.
Grunewald M, Kumar S, Sharife H, Volinsky E, Gileles-Hillel A, Licht T, Permyakova A, Hinden L, Azar S, Friedmann Y, Kupetz P, Tzuberi R, Anisimov A, Alitalo K, Horwitz M, Leebhoff S, Khoma OZ, Hlushchuk R, Djonov V, Abramovitch R, Tam J, Keshet E.
Grunewald M, et al.
Science. 2021 Jul 30;373(6554):eabc8479. doi: 10.1126/science.abc8479.
Science. 2021.
PMID: 34326210
Increasing VEGF signaling prevented age-associated capillary loss, improved organ perfusion and function, and extended life span. Healthier aging was evidenced by favorable metabolism and body composition and amelioration of aging-associated pathologies including he …
Increasing VEGF signaling prevented age-associated capillary loss, improved organ perfusion and function, and extended life span. Hea …