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Association of Brain Structure Changes and Cognitive Function With Combination Antiretroviral Therapy in HIV-Positive Individuals.
Sanford R, Fellows LK, Ances BM, Collins DL. Sanford R, et al. JAMA Neurol. 2018 Jan 1;75(1):72-79. doi: 10.1001/jamaneurol.2017.3036. JAMA Neurol. 2018. PMID: 29131878 Free PMC article.
IMPORTANCE: Despite the introduction of combination antiretroviral therapy (cART), HIV-associated neurocognitive disorders continue to be a problem for treated HIV-positive individuals. The cause of this impairment remains u …
IMPORTANCE: Despite the introduction of combination antiretroviral therapy (cART), HIV-associated neuroco …
Clinical and neuroimaging correlates of cognition in HIV.
Davies O, Haynes BI, Casey SJ, Gerbase S, Barker GJ, Pitkanen M, Kulasegaram R, Kopelman MD. Davies O, et al. J Neurovirol. 2019 Dec;25(6):754-764. doi: 10.1007/s13365-019-00763-w. Epub 2019 Jun 18. J Neurovirol. 2019. PMID: 31214916 Free PMC article.
This study investigated whether HIV-positive participants, stable on combined antiretroviral therapy (cART), showed cognitive impairments relative to HIV-negative controls; and whether clinical and neuroimaging factors correlated w …
This study investigated whether HIV-positive participants, stable on combined antiretroviral therapy (cAR …
Review of functional MRI in HIV: effects of aging and medication.
Hakkers CS, Arends JE, Barth RE, Du Plessis S, Hoepelman AI, Vink M. Hakkers CS, et al. J Neurovirol. 2017 Feb;23(1):20-32. doi: 10.1007/s13365-016-0483-y. Epub 2016 Oct 7. J Neurovirol. 2017. PMID: 27718211 Free PMC article. Review.
Blood oxygenated level dependent (BOLD) fMRI has shown to be a sensitive tool to detect abnormal brain function in an early stage and might therefore be useful to evaluate the effect of HIV infection on brain function. ...A few studies investiga …
Blood oxygenated level dependent (BOLD) fMRI has shown to be a sensitive tool to detect abnormal brain function in an early st …
Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy.
Cysique LA, Vaida F, Letendre S, Gibson S, Cherner M, Woods SP, McCutchan JA, Heaton RK, Ellis RJ. Cysique LA, et al. Neurology. 2009 Aug 4;73(5):342-8. doi: 10.1212/WNL.0b013e3181ab2b3b. Epub 2009 May 27. Neurology. 2009. PMID: 19474412 Free PMC article. Clinical Trial.
OBJECTIVE: To rigorously evaluate the time course of cognitive change in a cohort of individuals with HIV-associated neurocognitive disorders (HAND) initiating combination antiretroviral therapy (CART), and to investigate wh …
OBJECTIVE: To rigorously evaluate the time course of cognitive change in a cohort of individuals with HIV-ass
Changes in sleep quality and brain wave patterns following initiation of an efavirenz-containing triple antiretroviral regimen.
Moyle G, Fletcher C, Brown H, Mandalia S, Gazzard B. Moyle G, et al. HIV Med. 2006 May;7(4):243-7. doi: 10.1111/j.1468-1293.2006.00363.x. HIV Med. 2006. PMID: 16630036 Free article.
BACKGROUND: Initiation of efavirenz is commonly associated with sleep disturbances. Assessment of sleep using the electroencephalogram and electromyogram enables sleep staging to be performed and changes following the introduction of therapy to be evaluated. …
BACKGROUND: Initiation of efavirenz is commonly associated with sleep disturbances. Assessment of sleep using the electroencephalogra …
Reduced neural specificity in middle-aged HIV+ women in the absence of behavioral deficits.
Liu C, Wang C, Leclair M, Young M, Jiang X. Liu C, et al. Neuroimage Clin. 2014 Dec 13;8:667-75. doi: 10.1016/j.nicl.2014.12.003. eCollection 2015. Neuroimage Clin. 2014. PMID: 26288750 Free PMC article.
In the post combination antiretroviral therapy (cART) era, the prevalence of mild forms of HIV-associated neurocognitive disorders (HAND) in individuals with HIV-infection remains high. ...In contrast, conventional fMRI techniques …
In the post combination antiretroviral therapy (cART) era, the prevalence of mild forms of HIV-associated