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Association of Autism Spectrum Disorder With Prenatal Exposure to Medication Affecting Neurotransmitter Systems.
Janecka M, Kodesh A, Levine SZ, Lusskin SI, Viktorin A, Rahman R, Buxbaum JD, Schlessinger A, Sandin S, Reichenberg A. Janecka M, et al. JAMA Psychiatry. 2018 Dec 1;75(12):1217-1224. doi: 10.1001/jamapsychiatry.2018.2728. JAMA Psychiatry. 2018. PMID: 30383108 Free PMC article.
IMPORTANCE: Prenatal exposure to certain medications has been hypothesized to influence the risk of autism spectrum disorders (ASD). However, the underlying effects on the neurotransmitter systems have not been comprehensively asse …
IMPORTANCE: Prenatal exposure to certain medications has been hypothesized to influence the risk of autism sp
Valproic Acid and Propionic Acid Modulated Mechanical Pathways Associated with Autism Spectrum Disorder at Prenatal and Neonatal Exposure.
Sharma AR, Batra G, Saini L, Sharma S, Mishra A, Singla R, Singh A, Singh RS, Jain A, Bansal S, Modi M, Medhi B. Sharma AR, et al. CNS Neurol Disord Drug Targets. 2022;21(5):399-408. doi: 10.2174/1871527320666210806165430. CNS Neurol Disord Drug Targets. 2022. PMID: 34365961 Review.
Autism spectrum disorder (ASD) is a composite disorder of brain development with uncertain etiology and pathophysiology. ...Additionally, several important genes such as RELN, Lhx2, CREB, IL-6, NMDA, BDNF, etc., are also altered in ASD and involved in
Autism spectrum disorder (ASD) is a composite disorder of brain development with uncertain etiology and pathophy
Neuroglia in the autistic brain: evidence from a preclinical model.
Bronzuoli MR, Facchinetti R, Ingrassia D, Sarvadio M, Schiavi S, Steardo L, Verkhratsky A, Trezza V, Scuderi C. Bronzuoli MR, et al. Mol Autism. 2018 Dec 27;9:66. doi: 10.1186/s13229-018-0254-0. eCollection 2018. Mol Autism. 2018. PMID: 30603062 Free PMC article.
BACKGROUND: Neuroglial cells that provide homeostatic support and form defence of the nervous system contribute to all neurological disorders. We analyzed three major types of neuroglia, astrocytes, oligodendrocytes, and microglia in the brains of an animal model of aut
BACKGROUND: Neuroglial cells that provide homeostatic support and form defence of the nervous system contribute to all neurological d …
Chronic inhibition of astrocytic aquaporin-4 induces autistic-like behavior in control rat offspring similar to maternal exposure to valproic acid.
Davoudi S, Rahdar M, Hosseinmardi N, Behzadi G, Janahmadi M. Davoudi S, et al. Physiol Behav. 2023 Oct 1;269:114286. doi: 10.1016/j.physbeh.2023.114286. Epub 2023 Jul 2. Physiol Behav. 2023. PMID: 37402416
Social communication and interaction deficits, memory impairment, and anxiety-like behavior are characterized in many people identified with autism spectrum disorder (ASD). A thorough understanding of the specific aspects that contribute to the deficiencies …
Social communication and interaction deficits, memory impairment, and anxiety-like behavior are characterized in many people identified with …
Study of the serum levels of polyunsaturated fatty acids and the expression of related liver metabolic enzymes in a rat valproate-induced autism model.
Zhao G, Gao J, Liang S, Wang X, Sun C, Xia W, Hao Y, Li X, Cao Y, Wu L. Zhao G, et al. Int J Dev Neurosci. 2015 Aug;44:14-21. doi: 10.1016/j.ijdevneu.2015.04.350. Epub 2015 Apr 24. Int J Dev Neurosci. 2015. PMID: 25916973
To investigate whether the decreased level of serum polyunsaturated fatty acids (PUFAs) in patients with autism is associated with the expression of related liver metabolic enzymes, we selected rats that were exposed to valproic acid (VPA) on embryonic day 12.5 (E12 …
To investigate whether the decreased level of serum polyunsaturated fatty acids (PUFAs) in patients with autism is associated