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Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.
Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE; Alzheimer’s Disease Genetics Consortium; GERAD1 Consortium; EPIC-InterAct Consortium, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA. Østergaard SD, et al. PLoS Med. 2015 Jun 16;12(6):e1001841; discussion e1001841. doi: 10.1371/journal.pmed.1001841. eCollection 2015 Jun. PLoS Med. 2015. PMID: 26079503 Free PMC article.
BACKGROUND: Potentially modifiable risk factors including obesity, diabetes, hypertension, and smoking are associated with Alzheimer disease (AD) and represent promising targets for intervention. However, the causality of these …
BACKGROUND: Potentially modifiable risk factors including obesity, diabetes, hypertension, and smoking are as
Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis.
Larsson SC, Traylor M, Malik R, Dichgans M, Burgess S, Markus HS; CoSTREAM Consortium, on behalf of the International Genomics of Alzheimer’s Project. Larsson SC, et al. BMJ. 2017 Dec 6;359:j5375. doi: 10.1136/bmj.j5375. BMJ. 2017. PMID: 29212772 Free PMC article.
OBJECTIVE: To determine which potentially modifiable risk factors, including socioeconomic, lifestyle/dietary, cardiometabolic, and inflammatory factors, are associated with Alzheimer's disease. DESIGN: Mendelian
OBJECTIVE: To determine which potentially modifiable risk factors, including socioeconomic, lifestyle/dietary, c …
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