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Insights into the connection between cancer and alternative splicing.
Kim E, Goren A, Ast G. Kim E, et al. Trends Genet. 2008 Jan;24(1):7-10. doi: 10.1016/j.tig.2007.10.001. Epub 2007 Dec 3. Trends Genet. 2008. PMID: 18054115
Alu-containing exons are alternatively spliced.
Sorek R, Ast G, Graur D. Sorek R, et al. Genome Res. 2002 Jul;12(7):1060-7. doi: 10.1101/gr.229302. Genome Res. 2002. PMID: 12097342 Free PMC article.
Drug-targeting strategies for prostate cancer.
Ast G. Ast G. Curr Pharm Des. 2003;9(6):455-66. doi: 10.2174/1381612033391603. Curr Pharm Des. 2003. PMID: 12570809 Review.
The U1 snRNP base pairs with the 5' splice site within a penta-snRNP complex.
Malca H, Shomron N, Ast G. Malca H, et al. Mol Cell Biol. 2003 May;23(10):3442-55. doi: 10.1128/mcb.23.10.3442-3455.2003. Mol Cell Biol. 2003. PMID: 12724403 Free PMC article.
Boric acid reversibly inhibits the second step of pre-mRNA splicing.
Shomron N, Ast G. Shomron N, et al. FEBS Lett. 2003 Sep 25;552(2-3):219-24. doi: 10.1016/s0014-5793(03)00928-1. FEBS Lett. 2003. PMID: 14527690
AluGene: a database of Alu elements incorporated within protein-coding genes.
Dagan T, Sorek R, Sharon E, Ast G, Graur D. Dagan T, et al. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D489-92. doi: 10.1093/nar/gkh132. Nucleic Acids Res. 2004. PMID: 14681464 Free PMC article.
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