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Pretreatment Prevotella-to-Bacteroides ratio and markers of glucose metabolism as prognostic markers for dietary weight loss maintenance.
Hjorth MF, Christensen L, Kjølbæk L, Larsen LH, Roager HM, Kiilerich P, Kristiansen K, Astrup A. Hjorth MF, et al. Eur J Clin Nutr. 2020 Feb;74(2):338-347. doi: 10.1038/s41430-019-0466-1. Epub 2019 Jul 8. Eur J Clin Nutr. 2020. PMID: 31285554 Clinical Trial.
BACKGROUND/OBJECTIVES: Pre-treatment gut microbial Prevotella-to-Bacteroides (P/B) ratio and markers of glucose metabolism (i.e., fasting glucose and insulin) have been suggested as biomarkers for optimal weight management. ...
BACKGROUND/OBJECTIVES: Pre-treatment gut microbial Prevotella-to-Bacteroides (P/B) ratio and markers of glucose metabolism (i.e., fas …
Pretreatment Prevotella-to-Bacteroides ratio and salivary amylase gene copy number as prognostic markers for dietary weight loss.
Hjorth MF, Christensen L, Larsen TM, Roager HM, Krych L, Kot W, Nielsen DS, Ritz C, Astrup A. Hjorth MF, et al. Am J Clin Nutr. 2020 May 1;111(5):1079-1086. doi: 10.1093/ajcn/nqaa007. Am J Clin Nutr. 2020. PMID: 32034403 Clinical Trial.
OBJECTIVE: Based on analysis of a previously published study, we investigated the hypothesis that interaction between diet, Prevotella-to-Bacteriodes ratio (P/B ratio), and AMY1 CN influence weight change. ...
OBJECTIVE: Based on analysis of a previously published study, we investigated the hypothesis that interaction between diet, Prevotella
Microbial enterotypes in personalized nutrition and obesity management.
Christensen L, Roager HM, Astrup A, Hjorth MF. Christensen L, et al. Am J Clin Nutr. 2018 Oct 1;108(4):645-651. doi: 10.1093/ajcn/nqy175. Am J Clin Nutr. 2018. PMID: 30239555 Review.
A number of recent studies have found evidence that stratification of individuals according to 2 microbial enterotypes (dominance of either Prevotella or Bacteroides) may be useful in predicting responses to diets and drugs. ...Consequently, the enterotype potentially affe …
A number of recent studies have found evidence that stratification of individuals according to 2 microbial enterotypes (dominance of either …
[Personalised nutrition for weight loss in overweight patients].
Hjorth MF, Astrup A. Hjorth MF, et al. Ugeskr Laeger. 2018 May 28;180(22):V11170897. Ugeskr Laeger. 2018. PMID: 29808812 Free article. Review. Danish.
We have investigated fasting plasma glucose (and insulin) levels as well as the microbiota Prevotella/Bacteroides-ratio as prognostic markers of weight loss during periods of characterised dietary composition. ...
We have investigated fasting plasma glucose (and insulin) levels as well as the microbiota Prevotella/Bacteroides-ratio as prognostic …
Prevotella-to-Bacteroides ratio predicts body weight and fat loss success on 24-week diets varying in macronutrient composition and dietary fiber: results from a post-hoc analysis.
Hjorth MF, Blædel T, Bendtsen LQ, Lorenzen JK, Holm JB, Kiilerich P, Roager HM, Kristiansen K, Larsen LH, Astrup A. Hjorth MF, et al. Int J Obes (Lond). 2019 Jan;43(1):149-157. doi: 10.1038/s41366-018-0093-2. Epub 2018 May 17. Int J Obes (Lond). 2019. PMID: 29777234 Free PMC article. Clinical Trial.
BACKGROUND/OBJECTIVES: Individuals with high pre-treatment bacterial Prevotella-to-Bacteroides (P/B) ratio have been reported to lose more body weight on diets high in fiber than subjects with a low P/B ratio. ...
BACKGROUND/OBJECTIVES: Individuals with high pre-treatment bacterial Prevotella-to-Bacteroides (P/B) ratio have been reported to lose …
Prevotella Abundance Predicts Weight Loss Success in Healthy, Overweight Adults Consuming a Whole-Grain Diet Ad Libitum: A Post Hoc Analysis of a 6-Wk Randomized Controlled Trial.
Christensen L, Vuholm S, Roager HM, Nielsen DS, Krych L, Kristensen M, Astrup A, Hjorth MF. Christensen L, et al. J Nutr. 2019 Dec 1;149(12):2174-2181. doi: 10.1093/jn/nxz198. J Nutr. 2019. PMID: 31504699 Clinical Trial.
METHODS: We stratified 46 (19 men, 27 women; ages 30-65 y) healthy, overweight adults by baseline Prevotella-to-Bacteroides ratios and Prevotella abundances. Subjects with no Prevotella were analyzed separately (n = 24). ...No 6-wk changes in appetite sensati …
METHODS: We stratified 46 (19 men, 27 women; ages 30-65 y) healthy, overweight adults by baseline Prevotella-to-Bacteroides ratios an …
A Multi-omics Approach to Unraveling the Microbiome-Mediated Effects of Arabinoxylan Oligosaccharides in Overweight Humans.
Benítez-Páez A, Kjølbæk L, Gómez Del Pulgar EM, Brahe LK, Astrup A, Matysik S, Schött HF, Krautbauer S, Liebisch G, Boberska J, Claus S, Rampelli S, Brigidi P, Larsen LH, Sanz Y. Benítez-Páez A, et al. mSystems. 2019 May 28;4(4):e00209-19. doi: 10.1128/mSystems.00209-19. mSystems. 2019. PMID: 31138673 Free PMC article.
In addition to their bifidogenic effect, we observed that AXOS boost the proportion of Prevotella species. Metagenome analysis showed increases in the presence of bacterial genes involved in vitamin/cofactor production, glycan metabolism, and neurotransmitter biosynthesis …
In addition to their bifidogenic effect, we observed that AXOS boost the proportion of Prevotella species. Metagenome analysis showed …
Microbial enterotypes beyond genus level: Bacteroides species as a predictive biomarker for weight change upon controlled intervention with arabinoxylan oligosaccharides in overweight subjects.
Christensen L, Sørensen CV, Wøhlk FU, Kjølbæk L, Astrup A, Sanz Y, Hjorth MF, Benítez-Páez A. Christensen L, et al. Gut Microbes. 2020 Nov 9;12(1):1847627. doi: 10.1080/19490976.2020.1847627. Epub 2020 Dec 15. Gut Microbes. 2020. PMID: 33319645 Free PMC article. Clinical Trial.
In the present study, we have stratified the subjects participating in the intervention (n = 29) according to the baseline Prevotella-to-Bacteroides (P/B) ratios through a post-hoc analysis and applied a linear mixed model analysis to identify the influence of this P/B rat …
In the present study, we have stratified the subjects participating in the intervention (n = 29) according to the baseline Prevotella
Pre-treatment microbial Prevotella-to-Bacteroides ratio, determines body fat loss success during a 6-month randomized controlled diet intervention.
Hjorth MF, Roager HM, Larsen TM, Poulsen SK, Licht TR, Bahl MI, Zohar Y, Astrup A. Hjorth MF, et al. Int J Obes (Lond). 2018 Mar;42(3):580-583. doi: 10.1038/ijo.2017.220. Epub 2017 Sep 8. Int J Obes (Lond). 2018. PMID: 28883543 Free PMC article. Clinical Trial.
Participants were grouped into two discrete enterotypes by their relative abundance of Prevotella spp. divided by Bacteroides spp. (P/B ratio) obtained by quantitative PCR analysis. ...
Participants were grouped into two discrete enterotypes by their relative abundance of Prevotella spp. divided by Bacteroides spp. (P …