Asturias FJ - Search Results

1

Generation of a stable, aminotyrosyl radical-induced α2β2 complex of Escherichia coli class Ia ribonucleotide reductase.

Minnihan EC, Ando N, Brignole EJ, Olshansky L, Chittuluru J, Asturias FJ, Drennan CL, Nocera DG, Stubbe J. Minnihan EC, et al. Among authors: asturias fj. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3835-40. doi: 10.1073/pnas.1220691110. Epub 2013 Feb 19. Proc Natl Acad Sci U S A. 2013. PMID: 23431160 Free PMC article.

2

3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound.

Brignole EJ, Tsai KL, Chittuluru J, Li H, Aye Y, Penczek PA, Stubbe J, Drennan CL, Asturias F. Brignole EJ, et al. Elife. 2018 Feb 20;7:e31502. doi: 10.7554/eLife.31502. Elife. 2018. PMID: 29460780 Free PMC article.

3

Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase.

Ando N, Brignole EJ, Zimanyi CM, Funk MA, Yokoyama K, Asturias FJ, Stubbe J, Drennan CL. Ando N, et al. Among authors: asturias fj. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21046-51. doi: 10.1073/pnas.1112715108. Epub 2011 Dec 12. Proc Natl Acad Sci U S A. 2011. PMID: 22160671 Free PMC article.

4

Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.

Zimanyi CM, Ando N, Brignole EJ, Asturias FJ, Stubbe J, Drennan CL. Zimanyi CM, et al. Among authors: asturias fj. Structure. 2012 Aug 8;20(8):1374-83. doi: 10.1016/j.str.2012.05.009. Epub 2012 Jun 21. Structure. 2012. PMID: 22727814 Free PMC article.

5

Clofarabine targets the large subunit (α) of human ribonucleotide reductase in live cells by assembly into persistent hexamers.

Aye Y, Brignole EJ, Long MJ, Chittuluru J, Drennan CL, Asturias FJ, Stubbe J. Aye Y, et al. Among authors: asturias fj. Chem Biol. 2012 Jul 27;19(7):799-805. doi: 10.1016/j.chembiol.2012.05.015. Chem Biol. 2012. PMID: 22840768 Free PMC article.

6

Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer.

Ando N, Li H, Brignole EJ, Thompson S, McLaughlin MI, Page JE, Asturias FJ, Stubbe J, Drennan CL. Ando N, et al. Among authors: asturias fj. Biochemistry. 2016 Jan 19;55(2):373-81. doi: 10.1021/acs.biochem.5b01207. Epub 2016 Jan 4. Biochemistry. 2016. PMID: 26727048 Free PMC article.

7

Single-particle electron microscopy of animal fatty acid synthase describing macromolecular rearrangements that enable catalysis.

Brignole EJ, Asturias F. Brignole EJ, et al. Methods Enzymol. 2010;483:179-202. doi: 10.1016/S0076-6879(10)83009-5. Methods Enzymol. 2010. PMID: 20888475

8

Subunit architecture of general transcription factor TFIIH.

Gibbons BJ, Brignole EJ, Azubel M, Murakami K, Voss NR, Bushnell DA, Asturias FJ, Kornberg RD. Gibbons BJ, et al. Among authors: asturias fj. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1949-54. doi: 10.1073/pnas.1105266109. Epub 2012 Jan 20. Proc Natl Acad Sci U S A. 2012. PMID: 22308316 Free PMC article.

9

Conformational flexibility of metazoan fatty acid synthase enables catalysis.

Brignole EJ, Smith S, Asturias FJ. Brignole EJ, et al. Among authors: asturias fj. Nat Struct Mol Biol. 2009 Feb;16(2):190-7. doi: 10.1038/nsmb.1532. Epub 2009 Jan 18. Nat Struct Mol Biol. 2009. PMID: 19151726 Free PMC article.

10

A soluble α-synuclein construct forms a dynamic tetramer.

Wang W, Perovic I, Chittuluru J, Kaganovich A, Nguyen LT, Liao J, Auclair JR, Johnson D, Landeru A, Simorellis AK, Ju S, Cookson MR, Asturias FJ, Agar JN, Webb BN, Kang C, Ringe D, Petsko GA, Pochapsky TC, Hoang QQ. Wang W, et al. Among authors: asturias fj. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17797-802. doi: 10.1073/pnas.1113260108. Epub 2011 Oct 17. Proc Natl Acad Sci U S A. 2011. PMID: 22006323 Free PMC article.

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