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Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera.
Atkinson SC, Dogovski C, Newman J, Dobson RC, Perugini MA. Atkinson SC, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1537-41. doi: 10.1107/S1744309111038395. Epub 2011 Nov 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 22139160 Free PMC article.
The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum.
Dobson RC, Atkinson SC, Gorman MA, Newman JM, Parker MW, Perugini MA. Dobson RC, et al. Among authors: atkinson sc. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Mar 1;64(Pt 3):206-8. doi: 10.1107/S1744309108002819. Epub 2008 Feb 29. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18323610 Free PMC article.
Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen.
Burgess BR, Dobson RC, Bailey MF, Atkinson SC, Griffin MD, Jameson GB, Parker MW, Gerrard JA, Perugini MA. Burgess BR, et al. Among authors: atkinson sc. J Biol Chem. 2008 Oct 10;283(41):27598-603. doi: 10.1074/jbc.M804231200. Epub 2008 Aug 5. J Biol Chem. 2008. PMID: 18684709
Crystallization and preliminary X-ray analysis of dihydrodipicolinate synthase from Clostridium botulinum in the presence of its substrate pyruvate.
Atkinson SC, Dobson RC, Newman JM, Gorman MA, Dogovski C, Parker MW, Perugini MA. Atkinson SC, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Mar 1;65(Pt 3):253-5. doi: 10.1107/S1744309108039018. Epub 2009 Feb 14. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19255476 Free PMC article.
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax.
Voss JE, Scally SW, Taylor NL, Atkinson SC, Griffin MD, Hutton CA, Parker MW, Alderton MR, Gerrard JA, Dobson RC, Dogovski C, Perugini MA. Voss JE, et al. Among authors: atkinson sc. J Biol Chem. 2010 Feb 19;285(8):5188-95. doi: 10.1074/jbc.M109.038166. Epub 2009 Nov 30. J Biol Chem. 2010. PMID: 19948665 Free PMC article.
X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP.
Sivaraman KK, Oellig CA, Huynh K, Atkinson SC, Poreba M, Perugini MA, Trenholme KR, Gardiner DL, Salvesen G, Drag M, Dalton JP, Whisstock JC, McGowan S. Sivaraman KK, et al. Among authors: atkinson sc. J Mol Biol. 2012 Sep 28;422(4):495-507. doi: 10.1016/j.jmb.2012.06.006. Epub 2012 Jun 16. J Mol Biol. 2012. PMID: 22709581
Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine.
Atkinson SC, Dogovski C, Downton MT, Pearce FG, Reboul CF, Buckle AM, Gerrard JA, Dobson RC, Wagner J, Perugini MA. Atkinson SC, et al. PLoS One. 2012;7(6):e38318. doi: 10.1371/journal.pone.0038318. Epub 2012 Jun 25. PLoS One. 2012. PMID: 22761676 Free PMC article.
Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana.
Griffin MD, Billakanti JM, Wason A, Keller S, Mertens HD, Atkinson SC, Dobson RC, Perugini MA, Gerrard JA, Pearce FG. Griffin MD, et al. Among authors: atkinson sc. PLoS One. 2012;7(7):e40318. doi: 10.1371/journal.pone.0040318. Epub 2012 Jul 5. PLoS One. 2012. PMID: 22792278 Free PMC article.
Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from Agrobacterium tumefaciens.
Atkinson SC, Dogovski C, Dobson RC, Perugini MA. Atkinson SC, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Sep 1;68(Pt 9):1040-7. doi: 10.1107/S1744309112033052. Epub 2012 Aug 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22949190 Free PMC article.
Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.
Atkinson SC, Dogovski C, Downton MT, Czabotar PE, Dobson RC, Gerrard JA, Wagner J, Perugini MA. Atkinson SC, et al. Plant Mol Biol. 2013 Mar;81(4-5):431-46. doi: 10.1007/s11103-013-0014-7. Epub 2013 Jan 26. Plant Mol Biol. 2013. PMID: 23354837
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