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Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1.
Crowther MD, Dolton G, Legut M, Caillaud ME, Lloyd A, Attaf M, Galloway SAE, Rius C, Farrell CP, Szomolay B, Ager A, Parker AL, Fuller A, Donia M, McCluskey J, Rossjohn J, Svane IM, Phillips JD, Sewell AK. Crowther MD, et al. Among authors: Attaf M. Nat Immunol. 2020 Feb;21(2):178-185. doi: 10.1038/s41590-019-0578-8. Epub 2020 Jan 20. Nat Immunol. 2020. PMID: 31959982
The T-cell receptor is not hardwired to engage MHC ligands.
Holland SJ, Bartok I, Attaf M, Genolet R, Luescher IF, Kotsiou E, Richard A, Wang E, White M, Coe DJ, Chai JG, Ferreira C, Dyson J. Holland SJ, et al. Among authors: Attaf M. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):E3111-8. doi: 10.1073/pnas.1210882109. Epub 2012 Oct 17. Proc Natl Acad Sci U S A. 2012. PMID: 23077253 Free PMC article.
αβ T cell receptors as predictors of health and disease.
Attaf M, Huseby E, Sewell AK. Attaf M, et al. Cell Mol Immunol. 2015 Jul;12(4):391-9. doi: 10.1038/cmi.2014.134. Epub 2015 Jan 26. Cell Mol Immunol. 2015. PMID: 25619506 Free PMC article. Review.
The T cell antigen receptor: the Swiss army knife of the immune system.
Attaf M, Legut M, Cole DK, Sewell AK. Attaf M, et al. Clin Exp Immunol. 2015 Jul;181(1):1-18. doi: 10.1111/cei.12622. Epub 2015 May 14. Clin Exp Immunol. 2015. PMID: 25753381 Free PMC article. Review.
Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations.
Rius C, Attaf M, Tungatt K, Bianchi V, Legut M, Bovay A, Donia M, Thor Straten P, Peakman M, Svane IM, Ott S, Connor T, Szomolay B, Dolton G, Sewell AK. Rius C, et al. Among authors: Attaf M. J Immunol. 2018 Apr 1;200(7):2263-2279. doi: 10.4049/jimmunol.1700242. Epub 2018 Feb 26. J Immunol. 2018. PMID: 29483360 Free PMC article.
Optimized Peptide-MHC Multimer Protocols for Detection and Isolation of Autoimmune T-Cells.
Dolton G, Zervoudi E, Rius C, Wall A, Thomas HL, Fuller A, Yeo L, Legut M, Wheeler S, Attaf M, Chudakov DM, Choy E, Peakman M, Sewell AK. Dolton G, et al. Among authors: Attaf M. Front Immunol. 2018 Jun 29;9:1378. doi: 10.3389/fimmu.2018.01378. eCollection 2018. Front Immunol. 2018. PMID: 30008714 Free PMC article.
Peptide Super-Agonist Enhances T-Cell Responses to Melanoma.
Galloway SAE, Dolton G, Attaf M, Wall A, Fuller A, Rius C, Bianchi V, Theaker S, Lloyd A, Caillaud ME, Svane IM, Donia M, Cole DK, Szomolay B, Rizkallah P, Sewell AK. Galloway SAE, et al. Among authors: Attaf M. Front Immunol. 2019 Mar 13;10:319. doi: 10.3389/fimmu.2019.00319. eCollection 2019. Front Immunol. 2019. PMID: 30930889 Free PMC article.
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