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Efficient selection and characterization of mutants of a human cell line which are defective in mitochondrial DNA-encoded subunits of respiratory NADH dehydrogenase.
Hofhaus G, Attardi G. Hofhaus G, et al. Among authors: attardi g. Mol Cell Biol. 1995 Feb;15(2):964-74. doi: 10.1128/MCB.15.2.964. Mol Cell Biol. 1995. PMID: 7823960 Free PMC article.
A detailed molecular analysis of the six complex I-deficient mutants revealed that two of them exhibited a frameshift mutation in the ND4 gene, in homoplasmic or in heteroplasmic form, resulting in the complete or partial loss, respectively, of the ND4 subunit; two other mutants …
A detailed molecular analysis of the six complex I-deficient mutants revealed that two of them exhibited a frameshift mutation in the ND4 ge …
242 results