Aubin Y - Search Results

1

Comparative Analysis of One-Dimensional Protein Fingerprint by Line Shape Enhancement and Two-Dimensional ¹H,¹³C Methyl NMR Methods for Characterization of the Higher Order Structure of IgG1 Monoclonal Antibodies.

Elliott KW, Ghasriani H, Wikström M, Giddens JP, Aubin Y, Delaglio F, Marino JP, Arbogast LW. Elliott KW, et al. Among authors: aubin y. Anal Chem. 2020 May 5;92(9):6366-6373. doi: 10.1021/acs.analchem.9b05385. Epub 2020 Apr 14. Anal Chem. 2020. PMID: 32267681 Free PMC article.

2

Assessment of the three-dimensional structure of recombinant protein therapeutics by NMR fingerprinting: demonstration on recombinant human granulocyte macrophage-colony stimulation factor.

Aubin Y, Gingras G, Sauvé S. Aubin Y, et al. Anal Chem. 2008 Apr 1;80(7):2623-7. doi: 10.1021/ac7026222. Epub 2008 Mar 6. Anal Chem. 2008. PMID: 18321136

3

Interactions between the conserved hydrophobic region of the prion protein and dodecylphosphocholine micelles.

Sauvé S, Buijs D, Gingras G, Aubin Y. Sauvé S, et al. Among authors: aubin y. J Biol Chem. 2012 Jan 13;287(3):1915-22. doi: 10.1074/jbc.M111.279364. Epub 2011 Nov 29. J Biol Chem. 2012. PMID: 22128151 Free PMC article.

4

A single N-acetylgalactosamine residue at threonine 106 modifies the dynamics and structure of interferon α2a around the glycosylation site.

Ghasriani H, Belcourt PJ, Sauvé S, Hodgson DJ, Brochu D, Gilbert M, Aubin Y. Ghasriani H, et al. Among authors: aubin y. J Biol Chem. 2013 Jan 4;288(1):247-54. doi: 10.1074/jbc.M112.413252. Epub 2012 Nov 26. J Biol Chem. 2013. PMID: 23184955 Free PMC article.

5

Precision and robustness of 2D-NMR for structure assessment of filgrastim biosimilars.

Ghasriani H, Hodgson DJ, Brinson RG, McEwen I, Buhse LF, Kozlowski S, Marino JP, Aubin Y, Keire DA. Ghasriani H, et al. Among authors: aubin y. Nat Biotechnol. 2016 Feb;34(2):139-41. doi: 10.1038/nbt.3474. Nat Biotechnol. 2016. PMID: 26849514 Free PMC article. No abstract available.

6

Application of 2D-NMR with room temperature NMR probes for the assessment of the higher order structure of filgrastim.

Brinson RG, Ghasriani H, Hodgson DJ, Adams KM, McEwen I, Freedberg DI, Chen K, Keire DA, Aubin Y, Marino JP. Brinson RG, et al. Among authors: aubin y. J Pharm Biomed Anal. 2017 Jul 15;141:229-233. doi: 10.1016/j.jpba.2017.03.063. Epub 2017 Apr 4. J Pharm Biomed Anal. 2017. PMID: 28454057 Free PMC article.

7

Assessment of the higher order structure of Humira®, Remicade®, Avastin®, Rituxan®, Herceptin®, and Enbrel® by 2D-NMR fingerprinting.

Hodgson DJ, Ghasriani H, Aubin Y. Hodgson DJ, et al. Among authors: aubin y. J Pharm Biomed Anal. 2019 Jan 30;163:144-152. doi: 10.1016/j.jpba.2018.09.056. Epub 2018 Oct 1. J Pharm Biomed Anal. 2019. PMID: 30296716

8

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics.

Brinson RG, Marino JP, Delaglio F, Arbogast LW, Evans RM, Kearsley A, Gingras G, Ghasriani H, Aubin Y, Pierens GK, Jia X, Mobli M, Grant HG, Keizer DW, Schweimer K, Ståhle J, Widmalm G, Zartler ER, Lawrence CW, Reardon PN, Cort JR, Xu P, Ni F, Yanaka S, Kato K, Parnham SR, Tsao D, Blomgren A, Rundlöf T, Trieloff N, Schmieder P, Ross A, Skidmore K, Chen K, Keire D, Freedberg DI, Suter-Stahel T, Wider G, Ilc G, Plavec J, Bradley SA, Baldisseri DM, Sforça ML, Zeri ACM, Wei JY, Szabo CM, Amezcua CA, Jordan JB, Wikström M. Brinson RG, et al. Among authors: aubin y. MAbs. 2019 Jan;11(1):94-105. doi: 10.1080/19420862.2018.1544454. Epub 2018 Dec 22. MAbs. 2019. PMID: 30570405 Free PMC article.

9

Effects of Excipients on the Structure and Dynamics of Filgrastim Monitored by Thermal Unfolding Studies by CD and NMR Spectroscopy.

Ghasriani H, Frahm GE, Johnston MJW, Aubin Y. Ghasriani H, et al. Among authors: aubin y. ACS Omega. 2020 Dec 4;5(49):31845-31857. doi: 10.1021/acsomega.0c04692. eCollection 2020 Dec 15. ACS Omega. 2020. PMID: 33344838 Free PMC article.

10

Backbone and side-chain resonance assignments of the NISTmAb-scFv and antigen-binding study.

Ghasriani H, Ahmadi S, Hodgson DJ, Aubin Y. Ghasriani H, et al. Among authors: aubin y. Biomol NMR Assign. 2022 Oct;16(2):391-398. doi: 10.1007/s12104-022-10109-z. Epub 2022 Sep 9. Biomol NMR Assign. 2022. PMID: 36083574 Free PMC article.

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