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Characterization of beta-adrenoceptor antagonists as substrates and inhibitors of the drug transporter P-glycoprotein.
Bachmakov I, Werner U, Endress B, Auge D, Fromm MF. Bachmakov I, et al. Among authors: auge d. Fundam Clin Pharmacol. 2006 Jun;20(3):273-82. doi: 10.1111/j.1472-8206.2006.00408.x. Fundam Clin Pharmacol. 2006. PMID: 16671962
Aceclofenac spares cyclooxygenase 1 as a result of limited but sustained biotransformation to diclofenac.
Hinz B, Rau T, Auge D, Werner U, Ramer R, Rietbrock S, Brune K. Hinz B, et al. Among authors: auge d. Clin Pharmacol Ther. 2003 Sep;74(3):222-35. doi: 10.1016/S0009-9236(03)00167-X. Clin Pharmacol Ther. 2003. PMID: 12966366 Clinical Trial.
The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3.
Seithel A, Eberl S, Singer K, Auge D, Heinkele G, Wolf NB, Dörje F, Fromm MF, König J. Seithel A, et al. Among authors: auge d. Drug Metab Dispos. 2007 May;35(5):779-86. doi: 10.1124/dmd.106.014407. Epub 2007 Feb 12. Drug Metab Dispos. 2007. PMID: 17296622
The prostaglandin transporter OATP2A1 is expressed in human ocular tissues and transports the antiglaucoma prostanoid latanoprost.
Kraft ME, Glaeser H, Mandery K, König J, Auge D, Fromm MF, Schlötzer-Schrehardt U, Welge-Lüssen U, Kruse FE, Zolk O. Kraft ME, et al. Among authors: auge d. Invest Ophthalmol Vis Sci. 2010 May;51(5):2504-11. doi: 10.1167/iovs.09-4290. Epub 2009 Dec 17. Invest Ophthalmol Vis Sci. 2010. PMID: 20019365
Identification of drugs and drug metabolites as substrates of multidrug resistance protein 2 (MRP2) using triple-transfected MDCK-OATP1B1-UGT1A1-MRP2 cells.
Fahrmayr C, König J, Auge D, Mieth M, Fromm MF. Fahrmayr C, et al. Among authors: auge d. Br J Pharmacol. 2012 Mar;165(6):1836-1847. doi: 10.1111/j.1476-5381.2011.01672.x. Br J Pharmacol. 2012. PMID: 21923755 Free PMC article.
Interaction of the cardiovascular risk marker asymmetric dimethylarginine (ADMA) with the human cationic amino acid transporter 1 (CAT1).
Strobel J, Mieth M, Endress B, Auge D, König J, Fromm MF, Maas R. Strobel J, et al. Among authors: auge d. J Mol Cell Cardiol. 2012 Sep;53(3):392-400. doi: 10.1016/j.yjmcc.2012.06.002. Epub 2012 Jun 15. J Mol Cell Cardiol. 2012. PMID: 22705145
Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple-transfected cell line.
Fahrmayr C, König J, Auge D, Mieth M, Münch K, Segrestaa J, Pfeifer T, Treiber A, Fromm M. Fahrmayr C, et al. Among authors: auge d. Br J Pharmacol. 2013 May;169(1):21-33. doi: 10.1111/bph.12126. Br J Pharmacol. 2013. PMID: 23387445 Free PMC article.
N(1)-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin-trimethoprim interaction.
Müller F, Pontones CA, Renner B, Mieth M, Hoier E, Auge D, Maas R, Zolk O, Fromm MF. Müller F, et al. Among authors: auge d. Eur J Clin Pharmacol. 2015 Jan;71(1):85-94. doi: 10.1007/s00228-014-1770-2. Epub 2014 Oct 22. Eur J Clin Pharmacol. 2015. PMID: 25552403 Clinical Trial.
Simultaneous determination of aceclofenac and three of its metabolites in human plasma by high-performance liquid chromatography.
Hinz B, Auge D, Rau T, Rietbrock S, Brune K, Werner U. Hinz B, et al. Among authors: auge d. Biomed Chromatogr. 2003 Jun;17(4):268-75. doi: 10.1002/bmc.243. Biomed Chromatogr. 2003. PMID: 12833392 Clinical Trial.
Establishment of reference values for the lysine acetylation marker Nɛ-acetyllysine in small volume human plasma samples by a multi-target LC-MS/MS method.
Gessner A, Mieth M, Auge D, Chafai A, Müller F, Fromm MF, Maas R. Gessner A, et al. Among authors: auge d. Amino Acids. 2019 Sep;51(9):1259-1271. doi: 10.1007/s00726-019-02765-8. Epub 2019 Aug 6. Amino Acids. 2019. PMID: 31388851
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