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Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system.
Augustin HG, Koh GY, Thurston G, Alitalo K. Augustin HG, et al. Nat Rev Mol Cell Biol. 2009 Mar;10(3):165-77. doi: 10.1038/nrm2639. Nat Rev Mol Cell Biol. 2009. PMID: 19234476 Review.
Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats.
Fiedler U, Krissl T, Koidl S, Weiss C, Koblizek T, Deutsch U, Martiny-Baron G, Marmé D, Augustin HG. Fiedler U, et al. Among authors: augustin hg. J Biol Chem. 2003 Jan 17;278(3):1721-7. doi: 10.1074/jbc.M208550200. Epub 2002 Nov 9. J Biol Chem. 2003. PMID: 12427764
Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells.
Füller T, Korff T, Kilian A, Dandekar G, Augustin HG. Füller T, et al. Among authors: augustin hg. J Cell Sci. 2003 Jun 15;116(Pt 12):2461-70. doi: 10.1242/jcs.00426. Epub 2003 May 6. J Cell Sci. 2003. PMID: 12734395
EphB receptors and ephrinB ligands: regulators of vascular assembly and homeostasis.
Augustin HG, Reiss Y. Augustin HG, et al. Cell Tissue Res. 2003 Oct;314(1):25-31. doi: 10.1007/s00441-003-0770-9. Epub 2003 Aug 2. Cell Tissue Res. 2003. PMID: 12905065 Review.
The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies.
Fiedler U, Scharpfenecker M, Koidl S, Hegen A, Grunow V, Schmidt JM, Kriz W, Thurston G, Augustin HG. Fiedler U, et al. Among authors: augustin hg. Blood. 2004 Jun 1;103(11):4150-6. doi: 10.1182/blood-2003-10-3685. Epub 2004 Feb 19. Blood. 2004. PMID: 14976056
Expression of angiopoietin-2 in endothelial cells is controlled by positive and negative regulatory promoter elements.
Hegen A, Koidl S, Weindel K, Marmé D, Augustin HG, Fiedler U. Hegen A, et al. Among authors: augustin hg. Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1803-9. doi: 10.1161/01.ATV.0000140819.81839.0e. Epub 2004 Jul 29. Arterioscler Thromb Vasc Biol. 2004. PMID: 15284088
Angiogenesis in the female reproductive system.
Augustin HG. Augustin HG. EXS. 2005;(94):35-52. doi: 10.1007/3-7643-7311-3_3. EXS. 2005. PMID: 15617469 Review. No abstract available.
The Tie-2 ligand angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism.
Scharpfenecker M, Fiedler U, Reiss Y, Augustin HG. Scharpfenecker M, et al. Among authors: augustin hg. J Cell Sci. 2005 Feb 15;118(Pt 4):771-80. doi: 10.1242/jcs.01653. Epub 2005 Feb 1. J Cell Sci. 2005. PMID: 15687104
Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2.
Saharinen P, Kerkelä K, Ekman N, Marron M, Brindle N, Lee GM, Augustin H, Koh GY, Alitalo K. Saharinen P, et al. Among authors: augustin h. J Cell Biol. 2005 Apr 25;169(2):239-43. doi: 10.1083/jcb.200411105. J Cell Biol. 2005. PMID: 15851516 Free PMC article.
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