Austen M - Search Results

1

Neurturin and a GLP-1 Analogue Act Synergistically to Alleviate Diabetes in Zucker Diabetic Fatty Rats.

Trevaskis JL, Sacramento CB, Jouihan H, Ali S, Le Lay J, Oldham S, Bhagroo N, Boland BB, Cann J, Chang Y, O'Day T, Howard V, Reers C, Winzell MS, Smith DM, Feigh M, Barkholt P, Schreiter K, Austen M, Andag U, Thompson S, Jermutus L, Coghlan MP, Grimsby J, Dohrmann C, Rhodes CJ, Rondinone CM, Sharma A. Trevaskis JL, et al. Among authors: austen m. Diabetes. 2017 Jul;66(7):2007-2018. doi: 10.2337/db16-0916. Epub 2017 Apr 13. Diabetes. 2017. PMID: 28408435

2

Phenotype-first screening for the identification of novel drug targets.

Austen M, Dohrmann C. Austen M, et al. Drug Discov Today. 2005 Feb 15;10(4):275-82. doi: 10.1016/S1359-6446(05)03368-4. Drug Discov Today. 2005. PMID: 15708746 Review.

3

Inhibition of GSK3 promotes replication and survival of pancreatic beta cells.

Mussmann R, Geese M, Harder F, Kegel S, Andag U, Lomow A, Burk U, Onichtchouk D, Dohrmann C, Austen M. Mussmann R, et al. Among authors: austen m. J Biol Chem. 2007 Apr 20;282(16):12030-7. doi: 10.1074/jbc.M609637200. Epub 2007 Jan 22. J Biol Chem. 2007. PMID: 17242403 Free article.

4

9-cyano-1-azapaullone (cazpaullone), a glycogen synthase kinase-3 (GSK-3) inhibitor activating pancreatic beta cell protection and replication.

Stukenbrock H, Mussmann R, Geese M, Ferandin Y, Lozach O, Lemcke T, Kegel S, Lomow A, Burk U, Dohrmann C, Meijer L, Austen M, Kunick C. Stukenbrock H, et al. Among authors: austen m. J Med Chem. 2008 Apr 10;51(7):2196-207. doi: 10.1021/jm701582f. Epub 2008 Mar 18. J Med Chem. 2008. PMID: 18345612

5

Characterization of the transcriptional regulator YY1. The bipartite transactivation domain is independent of interaction with the TATA box-binding protein, transcription factor IIB, TAFII55, or cAMP-responsive element-binding protein (CPB)-binding protein.

Austen M, Lüscher B, Lüscher-Firzlaff JM. Austen M, et al. J Biol Chem. 1997 Jan 17;272(3):1709-17. doi: 10.1074/jbc.272.3.1709. J Biol Chem. 1997. PMID: 8999850 Free article.

6

Identification and characterization of specific DNA-binding complexes containing members of the Myc/Max/Mad network of transcriptional regulators.

Sommer A, Bousset K, Kremmer E, Austen M, Lüscher B. Sommer A, et al. Among authors: austen m. J Biol Chem. 1998 Mar 20;273(12):6632-42. doi: 10.1074/jbc.273.12.6632. J Biol Chem. 1998. PMID: 9506959 Free article.

7

YY1 can inhibit c-Myc function through a mechanism requiring DNA binding of YY1 but neither its transactivation domain nor direct interaction with c-Myc.

Austen M, Cerni C, Lüscher-Firzlaff JM, Lüscher B. Austen M, et al. Oncogene. 1998 Jul 30;17(4):511-20. doi: 10.1038/sj.onc.1201968. Oncogene. 1998. PMID: 9696045

8

Regulation of cell growth by the Myc-Max-Mad network: role of Mad proteins and YY1.

Austen M, Cerni C, Henriksson M, Hilfenhaus S, Lüscher-Firzlaff JM, Menkel A, Seelos C, Sommer A, Lüscher B. Austen M, et al. Curr Top Microbiol Immunol. 1997;224:123-30. doi: 10.1007/978-3-642-60801-8_12. Curr Top Microbiol Immunol. 1997. PMID: 9308235 Review. No abstract available.

9

Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP.

Vervoorts J, Lüscher-Firzlaff JM, Rottmann S, Lilischkis R, Walsemann G, Dohmann K, Austen M, Lüscher B. Vervoorts J, et al. Among authors: austen m. EMBO Rep. 2003 May;4(5):484-90. doi: 10.1038/sj.embor.embor821. EMBO Rep. 2003. PMID: 12776737 Free PMC article.

10

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.

Yu M, Schreek S, Cerni C, Schamberger C, Lesniewicz K, Poreba E, Vervoorts J, Walsemann G, Grötzinger J, Kremmer E, Mehraein Y, Mertsching J, Kraft R, Austen M, Lüscher-Firzlaff J, Lüscher B. Yu M, et al. Among authors: austen m. Oncogene. 2005 Mar 17;24(12):1982-93. doi: 10.1038/sj.onc.1208410. Oncogene. 2005. PMID: 15674325

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