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Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.
Cowell IG, Sondka Z, Smith K, Lee KC, Manville CM, Sidorczuk-Lesthuruge M, Rance HA, Padget K, Jackson GH, Adachi N, Austin CA. Cowell IG, et al. Among authors: austin ca. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8989-94. doi: 10.1073/pnas.1204406109. Epub 2012 May 21. Proc Natl Acad Sci U S A. 2012. PMID: 22615413 Free PMC article.
Self-association of chromo domain peptides.
Cowell IG, Austin CA. Cowell IG, et al. Among authors: austin ca. Biochim Biophys Acta. 1997 Feb 8;1337(2):198-206. doi: 10.1016/s0167-4838(96)00165-3. Biochim Biophys Acta. 1997. PMID: 9048896
Eukaryotic DNA topoisomerase II beta.
Austin CA, Marsh KL. Austin CA, et al. Bioessays. 1998 Mar;20(3):215-26. doi: 10.1002/(SICI)1521-1878(199803)20:3<215::AID-BIES5>3.0.CO;2-Q. Bioessays. 1998. PMID: 9631649 Review.
An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2, 1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells.
Padget K, Stewart A, Charlton P, Tilby MJ, Austin CA. Padget K, et al. Among authors: austin ca. Biochem Pharmacol. 2000 Sep 15;60(6):817-21. doi: 10.1016/s0006-2952(00)00402-0. Biochem Pharmacol. 2000. PMID: 10930536
174 results